33154

Dithizon

puriss. p.a., reag. Ph. Eur., ≥98% (chelatometric), for metal titration

• Synonym(e): Diphenylthiocarbazon
• Lineare Formel: C₆H₅NHNHCSN=NC₆H₅
• CAS-Nummer: 60-10-6
• Molekulargewicht: 256.33
• UNSPSC Code: 12352100
• NACRES: NA.21
• PubChem Substance ID: 329754465
• EC Number: 200-454-1
• Beilstein/REAXYS Number: 748838
• MDL number: MFCD00003025

Eigenschaften

• Quality Level: 200
• agency: USP/NF, reag. Ph. Eur.
• grade: puriss. p.a.
• assay: ≥98% (chelatometric)
• technique(s): titration: suitable
• impurities: ≤0.001% heavy metals (as Pb)
• ign. residue: ≤0.2% (as SO₄)
• mp: 168 °C (dec.) (lit.)
• absorption: ≥1450 at 605 nm
• SMILES string: S=C(NNc1ccccc1)\N=N\c2ccccc2
• InChI: 1S/C13H12N4S/c18-13(16-14-11-7-3-1-4-8-11)17-15-12-9-5-2-6-10-12/h1-10,14H,(H,16,18)/b17-15+
• InChI key: UOFGSWVZMUXXIY-BMRADRMJSA-N

Beschreibung

General description

Dithizone (Diphenylthiocarbazone) is used as chelating agent for zinc. It is widely used for the liquid-liquid and solid phase extraction of various metals since it forms stable complexes with the metals.

Application

Dithizone (Diphenylthiocarbazone) may be used for the in vitro characterization of differentiated pancreatic islets clusters in differentiated embryonic stem cell cultures, as it forms chelates with zinc present in huge quantities in pancreatic islets, thereby selectively staining them. It may be used to form complex with silver ions in the cloud point preconcentration step before the trace level quantification of silver by flame atomic absorption spectrometry.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves