MABN46

Anti-Chloride intracellular channel protein (CLIC1) Antibody, clone CPTC-CLIC1-1

clone CPTC-CLIC1, from mouse

• Synonym(e): chloride intracellular channel 1, Chloride channel ABP, RNCC protein, Nuclear chloride ion channel 27, nuclear chloride ion channel protein, Regulatory nuclear chloride ion channel protein, chloride intracellular channel protein 1
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: CPTC-CLIC1, monoclonal
• Speziesreaktivität: human
• Methode(n): immunohistochemistry: suitable; western blot: suitable
• Isotyp: IgG2aκ
• NCBI-Hinterlegungsnummer: NP_001279
• UniProt-Hinterlegungsnummer: O00299
• Versandbedingung: wet ice
• Angaben zum Gen: human ... CLIC1(1192)

Beschreibung

Allgemeine Beschreibung

Chloride intracellular channel protein 1 (CLIC1) is a part of the CLIC family of proteins. This family of proteins reconstitute in phospholipid vesicles and have been shown to have chloride channel action. CLIC1 may rotate between membrane-bound and soluble forms since it has been seen as a membrane protein and in the cytoplasm. When there is a lack of detergent, CLIC1 becomes membrane-bound and can act as an anion-selective channel. Recently, it has been shown that CLIC1 is required in angiogenesis and has a part in controlling integrin cell surface expression.

Immunogen

Full length recombinant protein corresponding to human CLIC1.
Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program.

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Signalübertragung & Neurowissenschaft

Anti-Chloride intracellular channel protein (CLIC1) Antibody, clone CPTC-CLIC1-1 detects level of Chloride intracellular channel protein (CLIC1) & has been published & validated for use in WB, IH.

Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (http://antibodies.cancer.gov/antibodies/detail/CPTC-CLIC1-2)

Qualität

Evaluated by Western Blot in human liver tissue lysate.

Western Blot Analysis: 0.25 µg/mL of this antibody detected CLIC1 on 10 µg of human liver tissue lysate.

Zielbeschreibung

~27 kDa observed

Physikalische Form

Protein G

Format: Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Human liver tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10-13 - German Storage Class 10 to 13