FCABS352A4

Milli-Mark^® Anti-Nanog-Alexa Fluor 488 Antibody, NT

Milli-Mark^®, from rabbit

• Synonym(e): Homeobox transcription factor Nanog, Nanog homeobox
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: ALEXA FLUOR^™ 488
• Clone: polyclonal
• Application: FACS
• Citations: 22

Eigenschaften

• biological source: rabbit
• Quality Level: 100
• conjugate: ALEXA FLUOR^™ 488
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• species reactivity (predicted by homology): mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
• manufacturer/tradename: Milli-Mark^®
• technique(s): flow cytometry: suitable
• isotype: IgG
• NCBI accession no.: NP_079141
• UniProt accession no.: Q9H9S0
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... NANOG(79923)

Beschreibung

General description

34 kDa Calculated

NANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency, i.e., these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm).
NANOG may be useful in the immunohistochemical diagnosis of tumors. NANOG is expressed in germ cells of the fetus and in some germ cell tumors of the gonads and central nervous system (CNS).

Immunogen

Epitope: N-terminus

Linear peptide from mouse Nanog.

Application

Milli-Mark Anti-Nanog-Alexa Fluor 488 Antibody, N-terminus is an antibody against Nanog-Alexa Fluor 488 for use in FC.

Research Category
Stem Cell Research

Research Sub Category
Pluripotent & Early Differentiation

Biochem/physiol Actions

Antibody recognizes NANOG.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal IgG conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA

Preparation Note

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
2102 Ep cells

Evaluated by flow cytometry using 2102 Ep cells

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable