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345757

Sigma-Aldrich

Anti-Ganglioside GM₁ Rabbit pAb

liquid, Calbiochem®

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

liquid

Enthält nicht

preservative

Speziesreaktivität (Voraussage durch Homologie)

all

Hersteller/Markenname

Calbiochem®

Lagerbedingungen

OK to freeze
avoid repeated freeze/thaw cycles

Isotyp

IgG

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

Anti-Ganglioside GM₁, rabbit polyclonal, recognizes ganglioside GM₁. Cross-reacts slightly with asialo-GM₁. ELISA and TLC immunoblotting.
Rabbit polyclonal antibody supplied as undiluted serum. Recognizes ganglioside GM1.
Recognizes ganglioside GM1. Cross-reacts slightly with asialo-GM1. Note: IB refers to TLC-IB.

Immunogen

Bovine
purified, bovine ganglioside GM₁

Anwendung

ELISA (see comments)

TLC Immunoblotting (1:1000, colormetric)

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

Undiluted serum.

Rekonstituierung

Following initial thaw, aliquot and freeze (-20°C).

Sonstige Hinweise

Cross-reacts slightly with asialo-GM1. Does not cross-react with other carbohydrate epitopes. Product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock. This antibody has also been reported to work for ELISA. Variables associated with assay conditions will dictate the optimal working dilution.
Yoshino, H., et al. 1993. J. Neurochem.61, 658.
Kusunoki, S., et al. 1987. Neurology37, 1795.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Aleksandra Somogyi et al.
International journal of molecular sciences, 19(2) (2018-02-23)
Juvenile neuronal ceroid lipofuscinosis (JNCL) is caused by mutations in the CLN3 gene. Most JNCL patients exhibit a 1.02 kb genomic deletion removing exons 7 and 8 of this gene, which results in a truncated CLN3 protein carrying an aberrant
Neha Singhal et al.
Skeletal muscle, 5, 3-3 (2015-02-24)
Cell surface glycans are known to play vital roles in muscle membrane stability and muscle disease, but to date, roles for glycans in muscle regeneration have been less well understood. Here, we describe a role for complex gangliosides synthesized by
Danny Galleguillos et al.
Journal of neuroinflammation, 19(1), 9-9 (2022-01-08)
Gangliosides are glycosphingolipids highly enriched in the brain, with important roles in cell signaling, cell-to-cell communication, and immunomodulation. Genetic defects in the ganglioside biosynthetic pathway result in severe neurodegenerative diseases, while a partial decrease in the levels of specific gangliosides

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