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Merck

16-246

Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488

clone LA1, Upstate®, from mouse

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Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR 488
Clone:
LA1, monoclonal
Application:
IF
Citations:
10
Technischer Dienst
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biological source

mouse

Quality Segment

conjugate

ALEXA FLUOR 488

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

LA1, monoclonal

species reactivity

human, mouse, rat

manufacturer/tradename

Upstate®

technique(s)

immunofluorescence: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... EGFR(1956)
mouse ... Egfr(13649)
rat ... Egf(25313)

General description

Included Negative Control: Catalog # 16-240, Alexa Fluor 488-conjugated Normal Mouse IgG.

Inhibits A431 cell growth. Recognizes an antigenic determinant located on the extracellular domain of the receptor.

Immunogen

Human A431 membrane proteins

Application

Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
This Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488 is validated for use in IF for the detection of EGFR.

Biochem/physiol Actions

external domain of EGF receptor on all human cells. Competes with EGF and TGF-α for binding on human cells. Recognizes both phosphorylated and non-phosphorylated human EGF receptors.

Preparation Note

1 year at 4°C from date of shipment

Analysis Note

Routinely evaluated by positive immunostaining for the EGF receptor in A431 cells.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Alexa Fluor is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Lagerklasse

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Global Trade Item Number

SKUGTIN
16-24604053252410642