07-1521

Anti-phospho-NDRG3 (Ser331) Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Protein NDRG3, Protein Ndr3
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: horse, mouse
• Speziesreaktivität (Voraussage durch Homologie): bovine (based on 100% sequence homology), equine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), rat (based on 100% sequence homology), human (based on 100% sequence homology)
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_038893
• UniProt-Hinterlegungsnummer: Q9QYF9
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: phosphorylation (pSer331)
• Angaben zum Gen: bovine ... Ndrg3(514399) ; chimpanzee ... Ndrg3(735544) ; human ... NDRG3(57446) ; mouse ... Ndrg3(29812) ; rat ... Ndrg3(296318)

Beschreibung

Allgemeine Beschreibung

NDGR3 is a member of the N-myc down-regulated gene (NDGR) family which includes NDGR1-4. NDGR3 is ubiquitously expressed but is abundant in the brain, testis, prostate, and ovary. The precise role of NDGR3 has not been elucidated; however, previous studies have suggested that NDGR3 may play a role in spermatogenesis in mice, and aberrant expression of NDGR3 may lead to the proliferation of prostate cancer cells. NDGR3-mediated tumor growth may be due to upregulation of various angiogenic chemokines such as chemokine ligands 1, 3, and 5, which promote angiogenesis in tumors.

Spezifität

This antibody recognizes NDRG3 phosphorylated at (Ser331).

Immunogen

Epitope: Phosphorylated (Ser331)

KLH-conjugated linear peptide corresponding to mouse NDRG3 phosphorylated at (Ser331).

Anwendung

Research Category
Zelluläre Signaltransduktion

Research Sub Category
Entwicklungsabhängige Signalübertragung

Detect phospho-NDRG3 (Ser331) using this Anti-phospho-NDRG3 (Ser331) Antibody validated for use in Western Blotting.

Qualität

Evaluated by Western Blot in mouse embryonic fibroblast cell lysates under multiple conditions (see image).

Western Blot Analysis: 0.1 µg/mL of this antibody detected NDRG3 on 10 µg of mouse embryonic fibroblast cell lysates under multiple conditions (see image).

Zielbeschreibung

~33 kDa observed

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Mouse embryonic fibroblast cell lysates under multiple conditions (see image).

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable