672084

(S)-2-(Aminomethyl)-1-Boc-pyrrolidin

97%

• Synonym(e): (S)-2-(Aminomethyl)-1-(tert.-butoxycarbonyl)-pyrrolidin, (S)-2-(Aminomethyl)-1-pyrrolidincarbonsäure-tert.-butylester
• Empirische Formel (Hill-System): C₁₀H₂₀N₂O₂
• CAS-Nummer: 119020-01-8
• Molekulargewicht: 200.28
• Beilstein: 8905233
• MDL-Nummer: MFCD03419257
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 329760455
• NACRES: NA.22

Eigenschaften

• Assay: ≥96.5% (GC); 96.5-103.5% (NT); 97%
• Form: solid
• Optische Reinheit: enantiomeric excess: ≥97.5% (GC)
• Lagertemp.: 2-8°C
• SMILES String: CC(C)(C)OC(=O)N1CCC[C@H]1CN
• InChI: 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(12)7-11/h8H,4-7,11H2,1-3H3/t8-/m0/s1
• InChIKey: SOGXYCNKQQJEED-QMMMGPOBSA-N

Beschreibung

Anwendung

(S)-2-(Aminomethyl)-1-Boc-pyrrolidine can be used as a building block to synthesize:

• Imidazo[1,2-b]pyridazine derivatives as potent IKKβ inhibitors.
• 1,2-dicarba-closo-dodecaborane (o-carborane) and 1,7-dicarba-closo-dodecaborane (m-carborane) derivatives as potential D₂ receptor antagonists.
• Pyrrolidine based Merrifield resin as a chiral organocatalyst for the asymmetric Michael addition reaction of ketones with nitrostyrenes.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H314
• P-Sätze: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges