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Merck

561053

Sigma-Aldrich

Diethyl-(2-oxobutyl)phosphonat

96%

Synonym(e):

(2-Oxobutyl)phosphonic acid diethyl ester, Diethyl propanoylmethylphosphonate

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About This Item

Lineare Formel:
(C2H5O)2PCH2COCH2CH3
CAS-Nummer:
Molekulargewicht:
208.19
MDL-Nummer:
UNSPSC-Code:
12352108
PubChem Substanz-ID:
NACRES:
NA.22

Assay

96%

Eignung der Reaktion

reaction type: C-C Bond Formation

Brechungsindex

n20/D 1.4360 (lit.)

Dichte

1.072 g/mL at 25 °C (lit.)

SMILES String

CCOP(=O)(CC(=O)CC)OCC

InChI

1S/C8H17O4P/c1-4-8(9)7-13(10,11-5-2)12-6-3/h4-7H2,1-3H3

InChIKey

GQBVFZDYDHGZPY-UHFFFAOYSA-N

Anwendung

Reactant for synthesis of:
  • Oxa(bicyclo)octanone for use in preparing cycloheptane annulated furans
  • Anatoxin-a and homoanatoxin via the Wittig reaction
  • α-Methylene-β-amino ketones
  • 2-Amino-5-phosphono- and 2-amino-4-(phosphonomethyl)thiophenes using the Gewald reaction
  • Aliphatic musk odorants
  • Oxoalkylphosphonates

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves


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Nina V Fuchs et al.
Stem cell research, 41, 101592-101592 (2019-11-08)
The Renpenning syndrome spectrum is a rare X-linked mental retardation syndrome characterized by intellectual disability, microcephaly, low stature, lean body and hypogonadism. Mutations in the polyglutamine tract binding protein 1 (PQBP1) locus are causative for disease. Here, we describe the
Katharina Hutter et al.
Molecular cell, 78(5), 876-889 (2020-06-06)
Many microRNAs (miRNAs) are generated from primary transcripts containing multiple clustered stem-loop structures that are thought to be recognized and cleaved by the Microprocessor complex as independent units. Here, we uncover an unexpected mode of processing of the bicistronic miR-15a-16-1
Vera Chesnokova et al.
Endocrinology, 160(6), 1439-1447 (2019-04-20)
DNA damage occurs as a result of environmental insults and aging and, if unrepaired, may lead to chromosomal instability and tumorigenesis. Because GH suppresses ataxia-telangiectasia mutated kinase phosphorylation, decreases DNA repair, and increases DNA damage accumulation, we elucidated whether GH
Seung Wook Yang et al.
Molecular cell, 77(6), 1206-1221 (2020-01-26)
Alternative polyadenylation (APA) contributes to transcriptome complexity by generating mRNA isoforms with varying 3' UTR lengths. APA leading to 3' UTR shortening (3' US) is a common feature of most cancer cells; however, the molecular mechanisms are not understood. Here
Felipe Henriques et al.
Cell reports, 32(5), 107998-107998 (2020-08-07)
Adipocytes deficient in fatty acid synthase (iAdFASNKO) emit signals that mimic cold exposure to enhance the appearance of thermogenic beige adipocytes in mouse inguinal white adipose tissues (iWATs). Both cold exposure and iAdFASNKO upregulate the sympathetic nerve fiber (SNF) modulator

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