402141

3-Formyl-6-isopropylchromon

99%

• Synonym(e): 6-Isopropyl-4-oxo-4H-1-benzopyran-3-carboxaldehyd
• Empirische Formel (Hill-System): C₁₃H₁₂O₃
• CAS-Nummer: 49619-58-1
• Molekulargewicht: 216.23
• MDL-Nummer: MFCD00192183
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24865052

Eigenschaften

• Assay: 99%
• mp (Schmelzpunkt): 98-100 °C (lit.)
• SMILES String: CC(C)c1ccc2OC=C(C=O)C(=O)c2c1
• InChI: 1S/C13H12O3/c1-8(2)9-3-4-12-11(5-9)13(15)10(6-14)7-16-12/h3-8H,1-2H3
• InChIKey: FRRYMYQANNFABF-UHFFFAOYSA-N
• Angaben zum Gen: human ... PTPN1(5770)

Beschreibung

Allgemeine Beschreibung

3-Formyl-6-isopropylchromone (6-Isopropyl-4-oxo-4H-1-benzopyran-3-carboxaldehyde, 6-Isopropyl-4-oxo-4H-chromene-3-carbaldehyde), a pyrazine (paradiazine) derivative, is a heterocyclic building block. It is a heterocyclic six-membered aromatic compound bearing nitrogen atoms at para positions.
Combustion calorimetric experiments have been conducted to evaluate the enthalpy of combustion of 3-formyl-6-isopropylchromone. Cytotoxic activity of 3-formyl-6-isopropylchromone against normal and tumor cells in vivo has been tested.

Anwendung

3-Formyl-6-isopropylchromone is the suitable reagent used in a study to investigate the multidrug resistance reversal by some 3- formylchromones in human colon cancer and mouse lymphoma cells transfected with the human MDR1 gene.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves