145998

2-Chinoxaloylchlorid

• Synonym(e): 2-Chinoxalincarbonylchlorid
• Empirische Formel (Hill-System): C₉H₅ClN₂O
• CAS-Nummer: 54745-92-5
• Molekulargewicht: 192.60
• EG-Nummer: 259-315-9
• MDL-Nummer: MFCD00006725
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24848755
• NACRES: NA.22

Eigenschaften

• mp (Schmelzpunkt): 113-115 °C (lit.)
• Funktionelle Gruppe: acyl chloride
• Lagertemp.: 2-8°C
• SMILES String: ClC(=O)c1cnc2ccccc2n1
• InChI: 1S/C9H5ClN2O/c10-9(13)8-5-11-6-3-1-2-4-7(6)12-8/h1-5H
• InChIKey: SOPDQKNXOCUBSR-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Quinoxaloyl chloride reacts with chiral α-hydroxy carboxylic acids to yield UV and fluorescent derivatives.

Anwendung

2-Quinoxaloyl chloride was used in the synthesis of novel DNA interactive quinoxaline-carbohydrate hybrids possessing disaccharides as the carbohydrate moieties.

Reactant involved in the synthesis of a variety of inhibitors including:

• Gelatinase inhibitors for cancer treatments
• mGluR5 non-competitve antagonists
• Heterocyclic analogs used as SIRT1 activators
• 3rd Generation multidrug resistance modulators

Reactant involved in preparation of PET ligants for breast cancer resistance protein imaging

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges