ZBTB33
zinc finger and BTB domain containing 33
Synonyme:
ZNF-kaiso, ZNF348
Spezies:
Human ZBTB33 (10009), Mouse Zbtb33 (56805), Rat Zbtb33 (501506), Domestic Rabbit ZBTB33 (100348939), domestic cat ZBTB33 (101086378), cow ZBTB33 (784871), dog ZBTB33 (100685062), Horse ZBTB33 (100062002), naked mole-rat Zbtb33 (101708806), Zebrafish zbtb33 (562507) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(10009) Summary: This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, May 2010]
- Mouse(56805) zinc finger and BTB domain containing 33
- Rat(501506) zinc finger and BTB domain containing 33
- Domestic Rabbit(100348939) zinc finger and BTB domain containing 33
- domestic cat(101086378) zinc finger and BTB domain containing 33
- cow(784871) zinc finger and BTB domain containing 33
- dog(100685062) zinc finger and BTB domain containing 33
- Horse(100062002) zinc finger and BTB domain containing 33
- naked mole-rat(101708806) zinc finger and BTB domain containing 33
- Zebrafish(562507) zinc finger and BTB domain containing 33
- chicken(422367) zinc finger and BTB domain containing 33
- domestic guinea pig(100713178) zinc finger and BTB domain containing 33
- sheep(101112197) zinc finger and BTB domain containing 33
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Kaiso Antibody, clone 6F, clone 6F, Upstate®, from mouse,
Speziesreaktivität
canine, chicken, hamster, human, monkey, mouse, rat
Anwendung
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-ZBTB33 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-ZBTB33 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-ZBTB33, (C-terminal) antibody produced in mouse, clone 2B2, ascites fluid,
Speziesreaktivität
human
Anwendung
ELISA
western blot
western blot
Monoclonal Anti-ZBTB33 antibody produced in mouse, clone 2B2, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
western blot
immunofluorescence
western blot