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SNCA

synuclein, alpha (non A4 component of amyloid precursor)

Synonyme:
NACP, PARK1, PARK4, PD1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6622) Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(20617) synuclein, alpha
  • Rat(29219) synuclein, alpha (non A4 component of amyloid precursor)
  • cow(282857) synuclein, alpha (non A4 component of amyloid precursor)
  • naked mole-rat(101700039) synuclein, alpha (non A4 component of amyloid precursor)
  • domestic cat(101091694) synuclein, alpha (non A4 component of amyloid precursor)
  • chicken(395393) synuclein, alpha (non A4 component of amyloid precursor)
  • sheep(100294604) synuclein, alpha (non A4 component of amyloid precursor)
  • dog(478478) synuclein, alpha (non A4 component of amyloid precursor)
  • Horse(100053270) synuclein, alpha (non A4 component of amyloid precursor)
  • domestic guinea pig(100725375) synuclein, alpha (non A4 component of amyloid precursor)

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-phospho-α-synuclein (Ser129) Antibody, clone PS129, ,
Speziesreaktivität
bovine, human, mouse, porcine, rat
Anwendung
ELISA
immunohistochemistry

western blot
Aggregierter Anti-α-Synuclein-Antikörper, Klon 5G4, clone 5G4, from mouse, purified by affinity chromatography,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry

western blot
Anti-Phospho-α-Synuklein(Ser129)-Antikörper, Klon 81A, clone 81A, from mouse,
Speziesreaktivität
human, mouse
Anwendung
electron microscopy
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-α-Synuclein antibody, Mouse monoclonal, clone Syn211, purified from hybridoma cell culture,
Speziesreaktivität
human, zebra finch
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-a-Synuclein, clone 10D2 Antibody, clone 10D2, from mouse, purified by affinity chromatography,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry

western blot

Proteins

Produktnummer
Beschreibung
Spezies
α-Synuklein human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Spezies
human
Synuclein, α, recombinant human, ,
Spezies
human
α-Synuclein A53T human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Spezies
human
α-Synuclein, Human, Recombinant, E. coli, ,
Spezies
human
α-Synuclein E46K human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SNCA (1),
Spezies
human
MISSION® esiRNA, targeting human SNCA (2),
Spezies
human