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Merck

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

Synonyme:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
human
Anwendung
western blot
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
Speziesreaktivität
rat
Anwendung
western blot
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, canine, guinea pig, horse, human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
western blot
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Flecainid -acetat (Salz), ,
Spezies
human
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Flecainidacetat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Flecainidacetat, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Flecainid-Acetat, British Pharmacopoeia (BP) Reference Standard,
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
Lamotrigin, ≥98%, powder,
Spezies
rat, human
Carbamazepin, powder,
Spezies
rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human SCN5A,
Spezies
human