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ACTN1

actinin, alpha 1

Synonyme:
BDPLT15
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(87) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(109711) actinin, alpha 1
  • Rat(81634) actinin, alpha 1
  • Domestic Rabbit(100341378) actinin, alpha 1
  • Zebrafish(560400) actinin, alpha 1
  • naked mole-rat(101711839) actinin, alpha 1
  • domestic guinea pig(100721342) actinin, alpha 1
  • cow(524770) actinin, alpha 1
  • chicken(373918) actinin, alpha 1
  • domestic cat(101097986) actinin, alpha 1
  • dog(480369) actinin, alpha 1
  • sheep(101122194) actinin, alpha 1

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-α Actinin antibody, Mouse monoclonal, clone BM-75.2, purified from hybridoma cell culture,
Speziesreaktivität
human
Anwendung
immunofluorescence
western blot
Anti-α-Actinin Antibody, clone AT6/172, clone AT6/172, Upstate®, from mouse,
Speziesreaktivität
human, mouse, rabbit
Anwendung
immunocytochemistry
western blot
Anti-ACTN1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-α Actinin Antibody, clone AT6/172 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-α-Actinin-1 Antibody, clone 2C17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey, mouse, rat
Anwendung
immunofluorescence
immunohistochemistry

western blot

Proteins

Produktnummer
Beschreibung
Spezies
LentiBrite α-actinin-GFP Lentiviral Biosensor, ,
Spezies
human
α-Actinin aus Hühner-Muskelmagen, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
Spezies
mouse, chicken, rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Actn1,
Spezies
mouse
MISSION® esiRNA, targeting human ACTN1,
Spezies
human