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MilliporeSigma

Glycobiology Profiling Tools

N-glycan structure with a wrench attached. Glycobiology profiling tools to support glycoprotein analysis, prep, modification and other glycobiology workflow needs.

Glycobiology profiling is critical to many areas of research. For example, glycosylation is one of the most common and impactful modifications found in biologic systems.  It is seen in the simplest of prokaryotes and the most complex multicellular organisms, attached to proteins, lipids, and even RNA playing roles in structure, function, and regulation.  As the knowledge base and methods evolve, scientists need the right tools for the job.  We are filling your toolbox with glycobiology reagents and tools like enzymes, resins, labels, and reagents to aid in the discovery and experimentation around glycobiology.

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Glycobiology Profiling Categories

To accommodate your glycobiology workflow needs, we offer a wide range of products for functional and structural analysis of glycans, including glycoprocessing and glycosylation enzymes, glycan labels, lectins, capture resins, standards, glycoproteins, and free oligosaccharides. This includes offerings of carbohydrate-recognizing proteins such as lectins and galectins, carbohydrate-active enzymes like glycosidases (exoglycosidases, endoglycosidases), and glycosyltransferases. Additionally, our GlycoProfile™ kits are a curated product line that have been developed to simplify common workflows including release and labeling of N-linked and O-linked glycans.

The glycobiology profiling tools we offer can be broken into these 4 categories:


Capture step of glycobiology workflow where enzyme is attaching to glycan structures.

CAPTURE

Release step of glycobiology workflow with a depiction of N-glycans and O-glycan structures.
Modify step of glycobiology workflow with a depiction of modifying glycan structures. Erlenmeyer flask in the middle of a circular process workflow with glycans linked to the left and glycans broken apart on the right.
Analyze step of glycobiology workflow with a depiction of N-linked glycan structures that are tagged with labels for analyzing.

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