U0750

Uracil

≥99.0%, synthetic (organic), powder

• Synonym(s): 2,4(1H,3H)-Pyrimidinedione, 2,4-Dihydroxypyrimidine, 2,4-Pyrimidinediol
• Empirical Formula (Hill Notation): C₄H₄N₂O₂
• CAS Number: 66-22-8
• Molecular Weight: 112.09
• NACRES: NA.51
• PubChem Substance ID: 24900618
• UNSPSC Code: 41106305
• EC Number: 200-621-9
• MDL number: MFCD00006016
• Beilstein/REAXYS Number: 507828
• Assay: ≥99.0%
• Biological source: synthetic (organic)
• Form: powder
• Solubility: 1 M NaOH: 50 mg/mL, clear to hazy, colorless to faint yellow or tan

Properties

• Product Name: Uracil, ≥99.0%
• biological source: synthetic (organic)
• Quality Segment: 300
• assay: ≥99.0%
• form: powder
• mp: >300 °C (lit.)
• solubility: 1 M NaOH: 50 mg/mL, clear to hazy, colorless to faint yellow or tan
• SMILES string: O=C1NC=CC(=O)N1
• InChI: 1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
• InChI key: ISAKRJDGNUQOIC-UHFFFAOYSA-N

Description

General description

Uracil belongs to the pyrimidine nucleobase family. It is naturally occurring and is an important and active part of RNA.[1]

Application

Uracil has been used as:

• a nucleotide standard to determine DNA methylation by high-performance liquid chromatography[2]
• a component of synthetic define medium for culturing Saccharomyces cerevisiae and its strain
• a component of the amino acid supplement to culture Bacillus sp[3]

Biochem/physiol Actions

Uracil and its derivatives play an integral part in medicinal chemistry for the synthesis of cancer, viral infections, autosomal recessive disorder, thyroid, and diabetic drugs.[1]

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)