Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

SML3563

Sigma-Aldrich

Complex 1 probe BAY-179

≥98% (HPLC)

Synonym(s):

2-(1-((1H-imidazo[4,5-b]pyridin-2-yl)methyl)piperidin-4-yl)-4-(benzofuran-2-yl)thiazole, 2-({4-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl}methyl)-1H-imidazo[4,5-b]-pyridine, 8-((4-(4-(7-Oxa-bicyclo[4.3.0]nona-1,3,5,8-tetraen-8-yl)-thiazol-2-yl)-piperidin-1-yl)-methyl)-2,7,9-triaza-bicyclo[4.3.0]nona-1(6),2,4,8-tetraene, BAY-179

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C23H21N5OS
CAS Number:
Molecular Weight:
415.51
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

SMILES string

C12=C(C=CC=N2)NC(CN3CCC(CC3)C4=NC(C5=CC6=CC=CC=C6O5)=CS4)=N1

Biochem/physiol Actions

Complex 1 probe BAY-179 is a cell penetrant, in vivo suitable, potent, selective, and species cross-reactive Complex I inhibitor.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jeffrey Mowat et al.
ACS medicinal chemistry letters, 13(3), 348-357 (2022-03-19)
Mitochondria are key regulators of energy supply and cell death. Generation of ATP within mitochondria occurs through oxidative phosphorylation (OXPHOS), a process which utilizes the four complexes (complex I-IV) of the electron transport chain and ATP synthase. Certain oncogenic mutations

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service