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N-Succinyl-Gly-Gly-Phe-p-nitroanilide

Name: N-Succinyl-Gly-Gly-Phe-<I>p</I>-nitroanilide
Brand: SIGMA

protease substrate, ≥98% (TLC), powder

Synonym(s):

Suc-Gly-Gly-Phe-PNA

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About This Item

Empirical Formula (Hill Notation):

C₂₃H₂₅N₅O₈

CAS Number:

68982-90-1

Molecular Weight:

499.47

NACRES:

NA.32

PubChem Substance ID:

24899502

UNSPSC Code:

12352204

EC Number:

273-486-7

MDL number:

MFCD00038721

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Properties

Product Name

N-Succinyl-Gly-Gly-Phe-p-nitroanilide, protease substrate

Quality Segment

200

assay

≥98% (TLC)

form

powder

solubility

acetic acid: 20 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

OC(=O)CCC(=O)NCC(=O)NCC(=O)NC(Cc1ccccc1)C(=O)Nc2ccc(cc2)N(=O)=O

InChI

1S/C23H25N5O8/c29-19(10-11-22(32)33)24-13-20(30)25-14-21(31)27-18(12-15-4-2-1-3-5-15)23(34)26-16-6-8-17(9-7-16)28(35)36/h1-9,18H,10-14H2,(H,24,29)(H,25,30)(H,26,34)(H,27,31)(H,32,33)

InChI key

CFYIUBWVKZQDOG-UHFFFAOYSA-N

Description

General description

Substrate for chymotrypsin and for S. griseus protease B.

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This Item	S2628	S4760	573462
Sigma-Aldrich S1899 N-Succinyl-Gly-Gly-Phe-p-nitroanilide	Sigma-Aldrich S2628 N-Succinyl-L-phenylalanine-p-nitroanilide	Sigma-Aldrich S4760 N-Succinyl-Ala-Ala-Ala-p-nitroanilide	Sigma-Aldrich 573462 Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide
description protease substrate	description protease substrate	description elastase substrate	description Sensitive chromogenic substrate for human leukocyte cathepsin G that is not reactive with elastase.
assay ≥98% (TLC)	assay ≥98% (TLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
solubility acetic acid: 20 mg/mL, clear, colorless to faintly yellow	solubility dioxane: 25 mg/mL, clear, colorless to faintly yellow	solubility DMF: 25 mg/mL, clear, colorless to light yellow	solubility DMSO: 100 mg/mL
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
form powder	form powder	form powder	form solid
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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