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H3760

Sigma-Aldrich

Hemoglobin from bovine blood

dried erythrocytes

Synonym(s):

Bovine hemoglobin, Hb, Methemoglobin

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About This Item

CAS Number:
9008-02-0
MDL number:
MFCD00131282
UNSPSC Code:
12352202
eCl@ss:
42030116
NACRES:
NA.61

biological source

bovine blood

Quality Level

200

form

dried erythrocytes

mol wt

Mr ~64500

solubility

0.6 M HCl: soluble 20 mg/mL

UniProt accession no.

P01966
P02070
P02081
P06642
P06643

storage temp.

2-8°C

Gene Information

cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)

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Application

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Oxygen transporter, NO scavenger
Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Quality

Methemoglobin and oxyhemoglobin content is not determined.

Caution

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000350747
0000352622
SLCH5426
SLCC6241
SLBT6447

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Van Phuc Nguyen et al.
Journal of biophotonics, 10(4), 577-588 (2016-05-03)
A variety of thermal therapeutic methods have been investigated to treat bladder tumors but often cause bowel injury and bladder wall perforation due to high treatment dosage and limited clinical margins. The objective of the current study is to develop
Glutamic acid reactivity in heated protein and protein-alginate mixtures.
C. G. Oates, d. A. Ledward, J. R. Mitchell and Hodgson.
International Journal of Food Science and Technology, 5, 477-483 (1987)
Michael Helton et al.
Biomedical optics express, 13(3), 1595-1608 (2022-04-14)
Measurements of time-resolved reflectance from a homogenous turbid medium can be employed to retrieve the absolute values of its optical transport coefficients. However, the uncertainty in the temporal shift of the experimentally determined instrument response function (IRF) with respect to
Byoungwook Bang et al.
Current protocols in pharmacology, 72, 5-5 (2016-03-21)
Animal models of experimentally induced inflammatory bowel disease (IBD) are useful for understanding more about the mechanistic basis of the disease, identifying new targets for therapeutic intervention, and testing novel therapeutics. This unit provides detailed protocols for five widely used
Michael Helton et al.
Biomedical optics express, 11(8), 4366-4378 (2020-09-15)
A heuristic method for estimating the reduced scattering coefficient (µs') of turbid media using time-resolved reflectance is presented. The technique requires measurements of the distributions of times-of-flight (DTOF) of photons arriving at two identical detection channels placed at unique distances
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Chromatograms

application for HPLC

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