1.06044

Dichloromethane

for liquid chromatography LiChrosolv^®

• Synonym(s): DCM, Methylene chloride, Methylene dichloride, Methylene chloride
• Linear Formula: CH₂Cl₂
• CAS Number: 75-09-2
• Molecular Weight: 84.93
• UNSPSC Code: 12191502
• NACRES: NA.03
• EC Index Number: 200-838-9
• MDL number: MFCD00000881
• Beilstein/REAXYS Number: 1730800
• Assay: ≥99.9% (GC)
• Technique(s): HPLC: suitable
• Bp: 39.8-40 °C (lit.)
• Vapor pressure: 24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

Properties

• vapor density: 2.9 (vs air)
• Quality Segment: 100
• vapor pressure: 24.45 psi ( 55 °C), 6.83 psi ( 20 °C)
• description: isocratic
• product line: LiChrosolv^®
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 1223 °F, 605 °C (DIN 51794)
• potency: 1600 mg/kg LD₅₀, oral (Rat), >2000 mg/kg LD₅₀, skin (Rat)
• contains: 2-methyl-2-butene as stabilizer
• expl. lim.: 22 %
• technique(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.01% Water
• evapn. residue: ≤5.0 mg/L
• transmittance: 240 nm, ≥70%, 245 nm, ≥90%, 260 nm, ≥99%
• refractive index: n20/D 1.424 (lit.)
• pH: 7 (20 °C)
• bp: 39.8-40 °C (lit.)
• mp: -95 °C, −95 °C (lit.)
• solubility: 20 g/L
• density: 1.325 g/mL at 25 °C (lit.)
• SMILES string: ClCCl
• storage temp.: 2-30°C
• InChI: 1S/CH2Cl2/c2-1-3/h1H2
• InChI key: YMWUJEATGCHHMB-UHFFFAOYSA-N

Description

General description

LiChrosolv^® solvents exhibit high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

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Application

Intended for HPLC and UHPLC-MS applications.

Features and Benefits

• suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
• specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)
  —ESI/APCI (+) < 2 ppb
  —ESI/APCI (-) < 10 ppb
• lowest impurity profile: for interference-free baselines (test 2)
• microfiltered through 0.2 μm filter (test 3) to provide:
  —a long lifespan to filters and mechanical parts of HPLC systems
  —reduced risk of column clogging
• packed in borosilicate glass bottles for minimum metal ion contaminations
• lowest levels of trace metal impurities for a minimum metal ion adduct formation
  —< 5ppb
• lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Purity (GC): ≥ 99.9 %
Identity (IR): conforms
Acidity: ≤ 0.0002 meq/g
Alkalinity: ≤ 0.0002 meq/g
Transmission (at 240 nm): ≥ 70 %
Transmission (at 245 nm): ≥ 90 %
Transmission (from 260 nm): ≥ 99 %
Evaporation residue: ≤ 5.0 mg/l
Water: ≤ 0.01 %
The product is stabilized with 2-Methyl-2-buten.
Filtered by 0.2 µm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H315,H319,H336,H351
• pcodes: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk: WGK 2