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52605

Sigma-Aldrich

Hexamethonium hydroxide solution

~0.1 M in H2O

Synonym(s):

N,N,N,N′,N′,N′-Hexamethylhexamethylenediammonium dihydroxide

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About This Item

Linear Formula:
(CH3)3N(OH)(CH2)6N(OH)(CH3)3
CAS Number:
Molecular Weight:
236.39
MDL number:
UNSPSC Code:
12352000
PubChem Substance ID:
NACRES:
NA.22

concentration

~0.1 M in H2O

impurities

≤0.01% halides (as bromide)

storage temp.

2-8°C

SMILES string

[OH-].[OH-].C[N+](C)(C)CCCCCC[N+](C)(C)C

InChI

1S/C12H30N2.2H2O/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H2/q+2;;/p-2

InChI key

GYLUMIIRFKDCKI-UHFFFAOYSA-L

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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P G Dinning et al.
American journal of physiology. Gastrointestinal and liver physiology, 303(1), G83-G92 (2012-05-05)
The rabbit colon consists of four distinct regions. The motility of each region is controlled by myogenic and neurogenic mechanisms. Associating these mechanisms with specific motor patterns throughout all regions of the colon has not previously been achieved. Three sections
Monalisa W Pereira et al.
Clinical and experimental pharmacology & physiology, 39(10), 869-877 (2012-09-28)
1. The 2 Hz train-of-four ratio (TOF(ratio)) is used to monitor the degree of patient curarization. Using a rat phrenic nerve-hemidiaphragm preparation, we showed that antinicotinic agents, such as hexamethonium, d-tubocurarine and pancuronium, but not cisatracurium, decreased contractions produced by
Jasna Twynstra et al.
Microvascular research, 84(2), 133-139 (2012-06-21)
We hypothesized that neuropeptide Y (NPY) exerts vasoconstrictor properties in sciatic nerve blood supply by a Y1 receptor (Y1R) mechanism. Using Doppler ultrasound (40MHz), we measured blood flow velocity through a sciatic nerve supply artery during infusions of NPY and/or
Hiroshi Hanamoto et al.
International journal of oral science, 4(1), 24-29 (2012-03-06)
Stimulation of the trigeminal nerve can elicit various cardiovascular and autonomic responses; however, the effects of anesthesia with pentobarbital sodium on these responses are unclear. Pentobarbital sodium was infused intravenously at a nominal rate and the lingual nerve was electrically
Simon Akerman et al.
Brain : a journal of neurology, 135(Pt 12), 3664-3675 (2012-10-16)
Trigeminal autonomic cephalalgias are highly disabling primary headache disorders, characterized by severe unilateral head pain and associated ipsilateral cranial autonomic features. There is limited understanding of their pathophysiology and how and where treatments act to reduce symptoms; this is significantly

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