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Merck

V800247

Sigma-Aldrich

Manganese(II) chloride

AR, ≥99%

Sinónimos:

Manganese dichloride, Sacchite

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About This Item

Fórmula lineal:
MnCl2
Número de CAS:
Peso molecular:
125.84
MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:

grade

AR

product line

Vetec

assay

≥99%

form

crystalline powder

pH

5.0-6.0 (5%)

mp

652 °C (lit.)

density

2.98 g/mL at 25 °C (lit.)

anion traces

sulfate (SO42-): ≤0.005%

cation traces

Ba: ≤0.01%
Ca: ≤0.03%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.01%
Mg: ≤0.005%
Na: ≤0.05%
Ni: ≤0.002%
Zn: ≤0.005%
heavy metals (as Pb): ≤0.0005%

SMILES string

Cl[Mn]Cl

InChI

1S/2ClH.Mn/h2*1H;/q;;+2/p-2

InChI key

GLFNIEUTAYBVOC-UHFFFAOYSA-L

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Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Brain

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
Anne Bertrand et al.
NeuroImage, 64, 693-702 (2012-09-11)
The impairment of axonal transport by overexpression or hyperphosphorylation of tau is well documented for in vitro conditions; however, only a few studies on this phenomenon have been conducted in vivo, using invasive procedures, and with contradictory results. Here we
A G Kanthasamy et al.
Toxicology letters, 214(3), 288-295 (2012-09-22)
The role of normal cellular prion protein (PrP) remains to be fully elucidated; however, the protein is crucial for the infection and progression of prion diseases. Recent evidence indicates that PrP is a metalloprotein since the octapeptide repeat sequences in
Jerome A Roth et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(7), 1143-1149 (2012-07-31)
Mutations in the parkin gene are linked to development of juvenile onset of Parkinson's disease and recent studies have reported that parkin can protect against increased oxidative stress and mitochondrial dysfunction caused by a variety of oxidative and toxic insults.
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related

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