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Documentos

1441301

USP

Metoprolol tartrate

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

Lopressor

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About This Item

Fórmula lineal:
(C15H25NO3)2 · C4H6O6
Número de CAS:
56392-17-7
Peso molecular:
684.81
MDL number:
MFCD00056257
UNSPSC Code:
41116107
PubChem Substance ID:
329750297
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

metoprolol

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

InChI key

YGULWPYYGQCFMP-CEAXSRTFSA-N

Gene Information

human ... ADRB1(153)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metoprolol tartrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Metoprolol Tartrate and Hydrochlorothiazide Tablets
  • Metoprolol Tartrate Compounded Oral Solution
  • Metoprolol Tartrate Compounded Oral Suspension
  • Metoprolol Tartrate Injection
  • Metoprolol Tartrate Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

Y0000145

Metoprolol impurity A, European Pharmacopoeia (EP) Reference Standard

1441243

Metoprolol Related Compound B, United States Pharmacopeia (USP) Reference Standard

1441254

Metoprolol Related Compound C, United States Pharmacopeia (USP) Reference Standard

1441265

Metoprolol Related Compound D, United States Pharmacopeia (USP) Reference Standard

1441298

Metoprolol succinate, United States Pharmacopeia (USP) Reference Standard

1441232

Metoprolol Related Compound A, United States Pharmacopeia (USP) Reference Standard

1441287

Metoprolol fumarate, United States Pharmacopeia (USP) Reference Standard

BP540

Metoprolol tartrate, British Pharmacopoeia (BP) Reference Standard

PHR9038

Metoprolol EP Impurity B, reference material

PHR9039

Metoprolol EP Impurity G, reference material

PHR9068

Metoprolol EP Impurity H, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR2509

Metoprolol Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR9101

Metoprolol EP Impurity E, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

PHR2510

Metoprolol Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2511

Metoprolol succinate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3046

Metoprolol Fumarate, pharmaceutical secondary standard, certified reference material

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Design and evaluation of mucoadhesive buccal drug delivery systems containing metoprolol tartrate.
Ramana, M. V., C. Nagda, and M. Himaja.
Indian Journal of Pharmaceutical Sciences, 69.4, 515-515 (2007)
C Narendra et al.
AAPS PharmSciTech, 7(2), E34-E34 (2006-06-27)
The purpose of the present study was to develop an optimized gastric floating drug delivery system (GFDDS) containing metoprolol tartrate (MT) as a model drug by the optimization technique. A 2(3) factorial design was employed in formulating the GFDDS with
Reply: Carvedilol versus metoprolol, but which metoprolol? Effect on inappropriate cardioverter-defibrillator therapy.
Martin H Ruwald et al.
Journal of the American College of Cardiology, 63(18), 1933-1934 (2014-02-04)
V M Raju et al.
Clinical radiology, 69(7), 739-744 (2014-05-16)
To evaluate the usage, safety, and efficacy of high-dose intravenous metoprolol for heart rate reduction in computer tomographic (CT) coronary angiography. As this was retrospective analysis of anonymous data, medical ethics committee approval was waived by the regional health research
Wenhuan Li et al.
Medicine, 93(28), e329-e329 (2014-12-20)
The sensitivity and specificity of 5 different image sets of dual-energy computed tomography (DECT) for the detection of first-pass myocardial perfusion defects have not systematically been compared using positron emission tomography (PET) as a reference standard. Forty-nine consecutive patients, with
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