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Merck
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Documentos clave

55505-U

Supelco

Discovery® Glycan SPE Tube

5 g, volume 60 mL, pk of 16

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About This Item

Código UNSPSC:
41115712
NACRES:
NB.21

Materiales

PE frit
polypropylene

Nivel de calidad

composición

, 5 g

envase

pk of 16

técnicas

solid phase extraction (SPE): suitable

volumen

60 mL

impurezas

<5% Water content

Matriz

polyamide resin base material

grupo activo de la matriz

amide, poly- phase

tamaño de partícula

50-160 μm

intervalo de pH

4.5-7.5(surface pH)

densidad aparente

0.2‑0.3 g/mL

técnica de separación

reversed phase

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Descripción general

Retention Mechanism: Reversed-phase
Sample Matrix Compatibility: Aqueous or methanolic solutions

  • Polyamide Resin: Particle Size: 50-160 μm, Surf pH: 4.5-7.5, Density: 0.2-0.3 cm3/g, Water Content: < 5 %
  • Useful for extracting gylcans from aqueous solutions.
  • Used to adsorb polar compounds (-OH groups, esp. phenolic compounds) from aqueous or methanolic solutions under the reversed-phase mechanism through strong hydrogen bonding between compound hydroxyl groups and amide groups of the resin
  • Also may be used for the extraction of tannins, chlorophyll, humic acid, pharmacologically active terpenoids, flavanoids, gallic acid, catechol A, protocatechuic acid, phloroglucinol, aromatic carboxylic acids, and nitroaromatic compounds
  • Irreversibly retains quinones.

Información legal

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Hsin-Yuan Chen et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(5), 1970-1986 (2018-09-21)
Uterine leiomyomas (ULs) are benign uterine tumors, and the most notable pathophysiologic feature of ULs is excessive accumulation of extracellular matrix (ECM). Fucoidan is a polysaccharide extracted from brown seaweeds that has a wide range of pharmacological properties, including anti-fibrotic
Weston B Struwe et al.
Cell reports, 24(8), 1958-1966 (2018-08-23)
Many broadly neutralizing antibodies (bnAbs) against HIV-1 recognize and/or penetrate the glycan shield on native, virion-associated envelope glycoprotein (Env) spikes. The same bnAbs also bind to recombinant, soluble trimeric immunogens based on the SOSIP design. While SOSIP trimers are close
Qi Gu et al.
Methods in molecular biology (Clifton, N.J.), 1758, 129-138 (2018-04-22)
Bioprinting provides an opportunity to produce three-dimensional (3D) tissues for biomedical research and translational drug discovery, toxicology, and tissue replacement. Here we describe a method for fabricating human neural tissue by 3D printing human neural stem cells with a bioink
Seok-Ho Yu et al.
The Journal of biological chemistry, 293(37), 14534-14544 (2018-07-28)
Deficiency in subunits of the conserved oligomeric Golgi (COG) complex results in pleiotropic defects in glycosylation and causes congenital disorders in humans. Insight regarding the functional consequences of this defective glycosylation and the identity of specific glycoproteins affected is lacking.
Qingxin Cui et al.
Frontiers in pharmacology, 9, 948-948 (2018-09-07)
Purpose: Understanding the distribution and interaction of the Traditional Chinese Medicines (TCMs) is an integral source of herbal drug discovery. An optimized radio-labeled method was explored that could conduct in situ biodistribution studies in animals. We evaluated the feasibility of

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