SAB4502029
Anti-NPY2R antibody produced in rabbit
affinity isolated antibody
Sinónimos:
NPY-Y2 receptor, NPY2-R, NPY2R, Neuropeptide Y receptor type 2
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
origen biológico
rabbit
conjugado
unconjugated
forma del anticuerpo
affinity isolated antibody
tipo de anticuerpo
primary antibodies
clon
polyclonal
Formulario
buffered aqueous solution
mol peso
antigen 42 kDa
reactividad de especies
human, mouse, rat
concentración
~1 mg/mL
técnicas
ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
wet ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... NPY2R(4887)
Descripción general
The NPY2R (neuropeptide Y receptor Y2) gene is mapped to human chromosome 4q32.1 and codes for a G-protein-coupled receptor. NPY2R is predominantly expressed in central nervous system including hypothalamus, brain stem, hippocampus, lateral septum and amygdala. NPY2 receptors are also distributed in the liver, spleen, intestine, adipose tissue and muscle.
Inmunógeno
The antiserum was produced against synthesized peptide derived from human NPY2R.
Immunogen Range: 1-50
Immunogen Range: 1-50
Acciones bioquímicas o fisiológicas
NPY2R (neuropeptide Y receptor Y2) acts as a presynaptic autoreceptor and heteroreceptor. It regulates the release of both endogenous NPY and neurotransmitters such as glutamate and γ–aminobutyric acid (GABA). NPY exerts its anxiolytic function via the NPY2R. Deletion of NPY2R results in retardation of the anticonvulsant actions of NPY. NPY2R plays an important role in the process of bone formation.
Características y beneficios
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Forma física
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
nwg
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Neuropeptide Y (NPY), a sympathetic neurotransmitter, is involved in various physiological functions, and its dysregulation is implicated in several neurodegenerative diseases. Glutamate excitotoxicity, endoplasmic reticulum (ER) stress, and oxidative stress are the common mechanisms associated with numerous neurodegenerative illnesses. The
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Food-derived biological signals are transmitted to the brain via peripheral nerves through the paracrine activity of gastrointestinal (GI) hormones. The signal transduction circuit of the brain-gut axis has been analyzed in animals; however, species-related differences and animal welfare concerns necessitate
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