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S4701

Sigma-Aldrich

Suplatast tosylate

≥98% (HPLC)

Sinónimos:

(+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate, IPD-1151T, ST

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About This Item

Fórmula empírica (notación de Hill):
C16H26SNO4 · C7H7SO3
Número de CAS:
94055-76-2
Peso molecular:
499.64
MDL number:
MFCD00867604
UNSPSC Code:
12352200
PubChem Substance ID:
329824551
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: >20 mg/mL

storage temp.

room temp

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2

InChI

1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)

InChI key

RYVJQEZJUFRANT-UHFFFAOYSA-N

Application

Suplatast tosylate may be used in immune-signaling studies.

Biochem/physiol Actions

Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H1 receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.3
Suplatast tosylate is an anti-allergy, cytokine modulator.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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The American journal of cardiology, 124(3), 325-333 (2019-06-04)
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Vitor Hugo Bezerra et al.
Sensors (Basel, Switzerland), 19(14) (2019-07-25)
Internet of Things (IoT) devices have become increasingly widespread. Despite their potential of improving multiple application domains, these devices have poor security, which can be explored by attackers to build large-scale botnets. In this work, we propose a host-based approach
Flemming K Nielsen et al.
BMC musculoskeletal disorders, 18(1), 510-510 (2017-12-06)
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Ana Moreno-Alcázar et al.
Trials, 18(1), 160-160 (2017-04-06)
Up to 60% of patients with bipolar disorder (BD) have a history of traumatic events, which is associated with greater episode severity, higher risk of comorbidity and higher relapse rates. Trauma-focused treatment strategies for BD are thus necessary but studies
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