P3513
Poly-L-lysine, succinylated
mol wt >50,000
Sinónimos:
Modified Lysine Copolymer
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About This Item
Productos recomendados
form
powder or solid
Quality Level
mol wt
>50,000
color
white to faint yellow
application(s)
cell analysis
storage temp.
−20°C
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Application
Succinylated poly-L-lysine has been used to bind (Gly)3-Arg-bradykinin to study its hydrolysis by brain endopeptidases and pancreatic proteinases.
Biochem/physiol Actions
An intermediate for coupling proteins to poly-L-lysine.
Poly-L-lysine is a cationic polymer. It is mainly used for immobilizing cells to glass substrates or negatively charged substrates.
Analysis Note
Molecular weight based on precursor poly-L-lysine viscosity. Also assayed by MALLS.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Los clientes también vieron
Topographical Pattern Dynamics in Passive Adhesion of Cell Membranes
Biophysical Journal, 87(5), 3547?3560-3547?3560 (2004)
Cancer biotherapy & radiopharmaceuticals, 26(6), 727-736 (2011-11-18)
Avidin-coupled monoclonal antibody MX35 (avidin-MX35) and astatine-211-labeled, biotinylated, succinylated poly-l-lysine ((211)At-B-PL(suc)) were administered in mice to assess potential efficacy as an intraperitoneal (i.p.) therapy for microscopic tumors. We aimed to establish a timeline for pretargeted radioimmunotherapy using these substances, and
Nucleic acids research, 27(15), 3090-3095 (1999-08-24)
DNA can be condensed with an excess of poly-cations in aqueous solutions forming stable particles of submicron size with positive surface charge. This charge surplus can be used to deposit alternating layers of polyanions and polycations on the surface surrounding
Effects of poly(L-lysine) substrates on attached Escherichia coli bacteria.
Langmuir, 26(4), 2639-2644 (2010)
British journal of cancer, 89(5), 937-943 (2003-08-28)
Conjugates between photosensitisers (PS) and charged polymeric carriers are under investigation for photodynamic therapy of cancer and may allow targeting to certain cell types or compartments in tumours. Covalent attachment of polyethylene glycol to macromolecules (pegylation) may alter their pharmacokinetics
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