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Merck

P0314

Sigma-Aldrich

Prostaglandin F methyl ester

~5 mg/mL in methyl acetate, ≥95% (HPLC)

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About This Item

Fórmula empírica (notación de Hill):
C21H36O5
Número de CAS:
Peso molecular:
368.51
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

assay

≥95% (HPLC)

concentration

~5 mg/mL in methyl acetate

storage temp.

−20°C

SMILES string

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)OCC

InChI

1S/C22H38O5/c1-3-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27-4-2/h6,9,14-15,17-21,23-25H,3-5,7-8,10-13,16H2,1-2H3/b9-6-,15-14+/t17-,18+,19+,20-,21+/m0/s1

InChI key

KRDFNHLEMLCWKD-GWSKAPOCSA-N

Biochem/physiol Actions

Constricts an isolated human smooth muscle; methyl ester form of prostaglandin F2α which is a luteolytic prostaglandin (induces parturition; pulmonary vasoconstrictor).

Packaging

Packaged under Argon.

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

15.0 °F

flash_point_c

-9.45 °C

ppe

Eyeshields, Faceshields, Gloves


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Mucha et al.
Prostaglandins, leukotrienes, and essential fatty acids, 65(5-6), 271-280 (2002-05-08)
This paper describes a new iodine-125 radioimmunoassay of 9alpha ,11beta-PGF2, and its use for the determination of urinary 9alpha,11beta-prostaglandin F2 after a selective one-step solid-phase extraction. The newly reported immunoassay is based on the use of 125I-tyrosyl methyl ester derivative
L Z Bito
Experimental eye research, 38(2), 181-194 (1984-02-01)
It has recently been shown that prostaglandin (PG)E2 or F2 alpha reduces the intraocular pressure (IOP) of cats and primates when applied topically to the eye in very small doses, and that reduced IOP can be maintained in these species
Y Goh et al.
Japanese journal of ophthalmology, 32(4), 471-480 (1988-01-01)
Studies were carried out of the effects of topically applied prostaglandin (PG) D2 and its metabolites and analogues on the intraocular pressure (IOP) in rabbits, and the results were compared with those of studies using PGE2 and F2 alpha. The
R N Prasad et al.
The Australian & New Zealand journal of obstetrics & gynaecology, 35(1), 52-54 (1995-02-01)
Prostaglandin analogues have proven to be safe and effective for second trimester pregnancy terminations when given by various routes. Of these, the intra-amniotic (IA) route has proven to be safer, especially in women with medical disorders, as it causes the
J Rydnert
Acta obstetricia et gynecologica Scandinavica, 65(2), 175-180 (1986-01-01)
The hysterometric technique has been designed to measure the pharmacological effect of active agents upon the human uterine muscle. The physiological background is the fact that smooth muscle contracts under the influence of mechanical stimulation. By applying hysterometry, the effects

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