N6377
Norharmane hydrochloride
crystalline
Sinónimos:
β-Carboline, 9H-Pyrido(3,4-b)indole
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About This Item
Productos recomendados
form
crystalline
color
yellow to green
storage temp.
2-8°C
SMILES string
Cl.c1ccc2c(c1)[nH]c3cnccc23
InChI
1S/C11H8N2.ClH/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10;/h1-7,13H;1H
InChI key
NEECSQBLLQEFLK-UHFFFAOYSA-N
Biochem/physiol Actions
Inhibitor of indoleamine 2,3-dioxygenase (IDO).
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Neuropharmacology, 85, 293-304 (2014-06-08)
Tobacco use is the leading cause of preventable death. Although the health risks are well known, cessation rates remain low. Whereas behavioral and neuroanatomical studies on tobacco addiction conventionally use nicotine, there is evidence that other constituents, such as monoamine
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 8(8), 1139-1149 (2009-07-30)
The photochemistry of norharmane (9H-pyrido[3,4-b]indole) in acidic (pH 5.0+/-0.1) and alkaline (pH 10.0+/-0.1) aqueous solutions was studied. The photochemical reactions were monitored by TLC, UV/VIS absorption spectroscopy, high-performance liquid chromatography (HPLC), electronic ionization-mass spectrometry (EI-MS), UV-laser desorption/ionization-time of flight-mass spectrometry
Molecular nutrition & food research, 53(12), 1496-1504 (2009-10-08)
Heterocyclic amines (HCAs) are potent mutagens/carcinogens to which humans are frequently exposed through the consumption of cooked meat and fish food. The effect of normal intake of HCAs and their role in the aetiology of human cancer is unknown. To
Journal of mass spectrometry : JMS, 44(2), 260-277 (2008-11-18)
The thermal stability of several commonly used crystalline matrix-assisted ultraviolet laser desorption/ionization mass spectrometry (UV-MALDI-MS) matrices, 2,5-dihydroxybenzoic acid (gentisic acid; GA), 2,4,6-trihydroxyacetophenone (THA), alpha-cyano-4-hydroxycinnamic acid (CHC), 3,5-dimethoxy-4-hydroxycinnamic acid (sinapinic acid; SA), 9H-pirido[3,4-b]indole (nor-harmane; nor-Ho), 1-methyl-9H-pirido[3,4-b]indole (harmane; Ho), perchlorate of nor-harmanonium
Journal of chromatography. A, 1192(2), 254-258 (2008-04-25)
The presence of cyclodextrins (CDs) in the mobile phase alters the chromatographic equilibria and induces a secondary chemical equilibrium associated to the chromatographic separation by HPLC. In this study the influence of the presence of CDs in the mobile phase
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