M3534
Anti-Mouse IgG (Fc specific) antibody produced in goat
2.0 mg/mL, affinity isolated antibody
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About This Item
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Productos recomendados
origen biológico
goat
Nivel de calidad
conjugado
unconjugated
forma del anticuerpo
affinity isolated antibody
tipo de anticuerpo
secondary antibodies
clon
polyclonal
concentración
2.0 mg/mL
técnicas
indirect ELISA: 1:15,000
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
modificación del objetivo postraduccional
unmodified
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Descripción general
IgG subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids.
Inmunógeno
Mouse IgG, Fc fragment
Aplicación
Anti-Mouse IgG (Fc specific) antibody has been used in:
- enzyme linked immunosorbent assay (ELISA)
- Ouchterlony double diffusion
- anti-drug antibody immunoassay
- immunoelectrophoresis
Acciones bioquímicas o fisiológicas
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice
Otras notas
Antibody adsorbed with human IgG and rat serum proteins
Forma física
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Nota de preparación
Adsorbed to reduce background with human or rat samples.
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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Development and validation of a standardized ELISA for the detection of soluble Fc-epsilon-RI in human serum
Lexmond W, et al.
Journal of Immunological Methods, 373(1-2), 192-199 (2011)
Nathan H Joh et al.
Journal of pharmaceutical sciences, 109(1), 845-853 (2019-10-20)
Silicone oil is a lubricant for prefilled syringes (PFS), a common primary container for biotherapeutics. Silicone oil particles (SiOP) shed from PFS are a concern for patients due to their potential for increased immunogenicity and therefore also of regulatory concern.
Universal immunoassay applied during early development of large molecules to understand impact of immunogenicity on biotherapeutic exposure
Bautista AC, et al.
The APPS Journal, 14(4), 843-849 (2012)
Integrating molecular detection and response to create self-signalling antibodies
Randle B, et al.
Biochemical and Biophysical Research Communications, 324(2), 504-510 (2004)
Christiano M V Barbosa et al.
Cell death discovery, 5, 135-135 (2019-09-26)
Annexin A1 (AnxA1) modulates neutrophil life span and bone marrow/blood cell trafficking thorough activation of formyl-peptide receptors (FPRs). Here, we investigated the effect of exogenous AnxA1 on haematopoiesis in the mouse. Treatment of C57BL/6 mice with recombinant AnxA1 (rAnxA1) reduced
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