M217

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α₁, α₃, α₅ Subunits) antibody produced in rat

clone mAb 35, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Anti-ACHR
• Número MDL: MFCD00677279
• Código UNSPSC: 12352203
• NACRES: NA.43

Propiedades

• origen biológico: rat
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: mAb 35, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human, chicken, eel
• no debe reaccionar con: Xenopus
• técnicas: immunohistochemistry (frozen sections): 1:3,000
• isotipo: IgG1
• Nº de acceso UniProt: CHRNA1
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CHRNA1(1134) , CHRNA3(1136) , CHRNA5(1138)

Descripción

Especificidad

Binds to the main immunogenic region on the extracellular surface of the α₁ subunit of muscle AChR′s and to homologous regions on α₃ and α₅ subunits of neuronal AChR′s. The epitope is located on the extracellular surface of the α₁ subunit of the muscle nicotinic acetylcholine receptor. The antibody binds to denatured chick α₅ AChR, but does not bind well to denatured α₃, α₄, α₇, α_8, and β₂. It may also bind β₃ due to homology of main immunogenic region. May be used to localize and detect the α₁, α₃ and α₅ subunits of the nicotinic acetylcholine receptor (AChR).

Inmunógeno

nicotinic acetylcholine receptor from the electric eel Electrophorus.

Forma física

Solution in 20 mM Na₃PO₄, pH 7.2, containing 150 mM NaCl and 0.05 % sodium azide.

Información legal

Sold with permission of the Salk Institute

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)