H8885

Hydroxyzine dihydrochloride

≥97%

• Fórmula empírica (notación de Hill): C₂₁H₂₇ClN₂O₂ · 2HCl
• Número de CAS: 2192-20-3
• Peso molecular: 447.83
• EC Number: 218-586-3
• MDL number: MFCD00058200
• UNSPSC Code: 12161501
• PubChem Substance ID: 24895830
• NACRES: NA.77

Propiedades

• Quality Level: 200
• assay: ≥97%
• form: powder
• solubility: H₂O: soluble; alcohol: soluble; chloroform: soluble
• SMILES string: Cl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
• InChI: 1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
• InChI key: ANOMHKZSQFYSBR-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Descripción

General description

Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist.[1]

Application

Hydroxyzine dihydrochloride has been used in the study of comparative anxiolytic activity of various drugs in experimental models of rats.[2]

Biochem/physiol Actions

Hydroxyzine dihydrochloride (HDH) is used to regulate anxiety. It is also used to treat bronchial asthma and to relax patients before surgery.[1]

Información de seguridad

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H336,H361d
• pcodes: P202 - P261 - P264 - P271 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves