G2785

Glycitein

≥97% (HPLC)

• Sinónimos: 4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein
• Fórmula empírica (notación de Hill): C₁₆H₁₂O₅
• Número de CAS: 40957-83-3
• Peso molecular: 284.26
• Número MDL: MFCD00016679
• Código UNSPSC: 41106305
• ID de la sustancia en PubChem: 329799906
• NACRES: NA.51

Propiedades

• origen biológico: synthetic (organic)
• Nivel de calidad: 100
• Ensayo: ≥97% (HPLC)
• Formulario: powder
• solubilidad: DMF: 1 mg/mL, clear, colorless to faintly yellow
• temp. de almacenamiento: −20°C
• cadena SMILES: COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3
• InChI: 1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3
• Clave InChI: DXYUAIFZCFRPTH-UHFFFAOYSA-N

Descripción

Aplicación

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine.[1] It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.[2]

Acciones bioquímicas o fisiológicas

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein possesses weak estrogenic activity than other soy isoflavones.[3]

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)