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Merck

F9557

Sigma-Aldrich

FSL-B(tri)

Sinónimos:

FSL-B(GALa3[Fa2]GALb)-SA1-L1

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About This Item

Fórmula empírica (notación de Hill):
C68H122N2NaO25P
Peso molecular:
1421.66
UNSPSC Code:
12352201
NACRES:
NA.25

assay

≥95% (TLC)

Quality Level

form

solid

storage temp.

−20°C

Application

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. Cells modified with KODE constructs are known as kodecytes and usually maintain their normal vitality and functionality.

FSL-B(tri) has been specifically designed to create live cells (kodecytes) expressing blood group B antigens but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces. This product can be used to attach reproducible and controlled levels of blood group B antigens (generic B due to its trisaccharide structure) to group O or A erythrocytes. These kodecytes will react with most anti-B blood grouping reagents including polyclonal reagents.
All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. FSL-B(tri) has been specifically designed to create live cells (kodecytes) expressing blood group B antigens but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces.
FSL-B(tri) has been used to modify cell or virion surfaces with markers.[1]

Other Notes

FSL-B(tri) is a KODE technology construct designed to label hydrophobic surfaces including living cells with blood group B trisaccharide. All KODE FSL constructs consist of three essential designable features: a functional component (F), a spacer (S), and a diacyl lipid (L). FSL-B(tri) is comprised of the blood group B trisaccharide Galα3(Fucα2)Galβ representing F, conjugated via an O(CH2)3NH spacer (SA1) to an activated adipate derivative of dioleoyl­phos­pha­tidyl­ethanol­amine (L1).

Legal Information

KODE Constructs are supplied by KODE Biotech Materials Limited under license from KODE Biotech Limited.
KODE is a trademark of KODE Biotech Ltd.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Visite la Librería de documentos

FSL Constructs: A Simple Method for Modifying Cell/Virion Surfaces with a Range of Biological Markers Without Affecting their Viability
D.A. Blake
Journal of Visualized Experiments (2011)

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