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Croton oil

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About This Item

Número de CAS:
8001-28-3
MDL number:
MFCD00130880
UNSPSC Code:
12352211
NACRES:
NA.25

biological source

plant (Croton tiglium L)

form

viscous liquid

density

0.94 g/mL at 25 °C (lit.)

functional group

ester

lipid type

oils

shipped in

ambient

storage temp.

room temp

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General description

Croton oil is a toxic viscous liquid extracted from seeds of Croton tiglium. It is pale yellow to brown in color and is transparent in nature. Croton oil has a strong irritant property and is used along with phenol in some chemical peels. It also has a tumor promoting ability.
Croton oil is extracted from Croton tiglium L. It consists of crotonoleic acid, crotonic acid, crotonyl alcohol, crotonyl alcohol bisester and crotonyl alcohol trisester. Croton oil acts as a stimulant in the skin and mucosal inflammation. It is associated with allergic contact dermatitis (ACD) and skin carcinoma. Croton oil functions as a skin peeling agent.

application

Croton oil has been used to induce acute skin inflammation.
Croton oil has been used to induce inflammation in mouse ears.

Other Notes

Essential oil rich in glycerides of saturated fatty acids, and in phorbol esters.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

165.2 °F - closed cup

flash_point_c

74 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Thekkuttuparambil Ananthanarayanan Ajith et al.
Journal of experimental therapeutics & oncology, 9(3), 207-215 (2011-11-11)
The roles of 7,12-dimethylbenz[a]anthracene (DMBA), a polycyclic aromatic hydrocarbon (PAH), and 12-O-tetradecanoylphorbol-13-acetate (TPA) a skin tumor promoter present in croton oil, are clearly implicated in the formation of skin papilloma. The effect of ethyl acetate extract of Phellinus rimosus, a
Sulaiman Hamizah et al.
Asian Pacific journal of cancer prevention : APJCP, 13(6), 2533-2539 (2012-09-04)
Annona muricata L (Annonaceae), commonly known as soursop has a long, rich history in herbal medicine with a lengthy recorded indigenous use. It had also been found to be a promising new anti-tumor agent in numerous in vitro studies. The
The inhibition of croton oil-promoted mouse skin tumorigenesis by steroid hormones
Belman S and Troll W
Cancer Research, 32(3), 450-454 (1972)
Phillip R Langsdon et al.
Facial plastic surgery : FPS, 28(1), 116-125 (2012-03-16)
Chemexfoliation is an excellent method to reduce facial rhytids. For 25 years, we have used the traditional formula as described by T. J. Baker but with a moist healing technique rather than a tape mask. We have found the peel
Heparanase expression in B16 melanoma cells and peripheral blood neutrophils before and after extravasation detected by novel anti-mouse heparanase monoclonal antibodies
Komatsu N, et al.
Journal of Immunological Methods, 331(1-2), 82-93 (2008)
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