C3130

Cortisone 21-acetate

≥99%

• Sinónimos: 17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione, 4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate
• Fórmula empírica (notación de Hill): C₂₃H₃₀O₆
• Número de CAS: 50-04-4
• Peso molecular: 402.48
• Beilstein/REAXYS Number: 2067543
• EC Number: 200-006-5
• MDL number: MFCD00003609
• UNSPSC Code: 51111800
• PubChem Substance ID: 24278306
• NACRES: NA.77

Propiedades

• biological source: synthetic (organic)
• Quality Level: 200
• sterility: non-sterile
• assay: ≥99%
• form: powder
• mp: 237-240 °C (lit.)
• solubility: chloroform: 50 mg/mL, clear, colorless to faintly yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1
• InChI key: ITRJWOMZKQRYTA-RFZYENFJSA-N
• Gene Information: human ... FNTA(2339) , NR3C1(2908)

Descripción

General description

Cortisone 21-acetate is a prodrug,[1] which has glucocorticoid and mineralocorticoid properties.[2] It is used as a therapeutic option for glucocorticoid replacement.[1]

Application

Cortisone 21-acetate has been used to study its effects in metastasis and phagocytic activity.[3]

Información de seguridad

• pictograms: GHS08
• signalword: Warning
• hcodes: H361d
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)