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C0742

Sigma-Aldrich

CKI-7 dihydrochloride

≥98% (HPLC), solid, CK1 inhibitor

Sinónimos:

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C11H12ClN3O2S · 2HCl
Número de CAS:
1177141-67-1
Peso molecular:
358.67
MDL number:
MFCD00897689
UNSPSC Code:
12352200
PubChem Substance ID:
24724430
NACRES:
NA.77

product name

CKI-7 dihydrochloride, ≥98% (HPLC), solid

Quality Level

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to light tan

solubility

H2O: >5 mg/mL

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H

InChI key

JUAVTXYOCISSSL-UHFFFAOYSA-N

Biochem/physiol Actions

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

Caution

Material is hygroscopic

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

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