Following reconstitution at 25 mg/mL in 0.1 M Acetic acid, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C. The stability of dilute solutions has not been determined, however, Bradykinin fragment 1 - 7, (B4181) is part of a set of standards for Maldi-MS calibration (MSCAL1). In this application, the solution is diluted to 10 pmol/uL and stored at -20°C for 1 month. One may infer that dilute solutions of the whole molecule would be comparably stable when diluted and stored frozen.
B3259
Bradykinin acetate salt
powder, ≥98% (HPLC)
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1 MG
US$ 80,10
5 MG
US$ 108,00
10 MG
US$ 163,00
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US$ 330,00
100 MG
US$ 1.090,00
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1 MG
US$ 80,10
5 MG
US$ 108,00
10 MG
US$ 163,00
25 MG
US$ 330,00
100 MG
US$ 1.090,00
About This Item
Fórmula empírica (notación de Hill):
C50H73N15O11 · xC2H4O2
Número de CAS:
Peso molecular:
1060.21 (free base basis)
Número CE:
Número MDL:
Código UNSPSC:
12352106
NACRES:
NA.32
Productos recomendados
grado
for analytical purposes
Ensayo
≥98% (HPLC)
Formulario
powder
condiciones de almacenamiento
desiccated
color
white
solubilidad
0.1 M acetic acid: 25 mg/mL, clear, colorless
Nº de acceso UniProt
temp. de almacenamiento
−20°C
cadena SMILES
N2([C@@H](CCC2)C(=O)NCC(=O)N[C@@H](Cc5ccccc5)C(=O)N[C@@H](CO)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)C(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CCCN=C(N)N
InChI
1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
Clave InChI
QXZGBUJJYSLZLT-FDISYFBBSA-N
Información sobre el gen
human ... KNG1 (includes EG:3827)
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Categorías relacionadas
Amino Acid Sequence
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
Aplicación
Acciones bioquímicas o fisiológicas
Activates pain receptors; induces smooth muscle contraction; activates Ca2+-dependent nitric oxide synthetase; increases capillary permeability.
Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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How should a solution of bradykinin acetate salt in 0.1M acetic acid be stored? Can it be further diluted in an aqueous buffer?
1 answer-
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