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A3352

Acyl-coenzyme A Synthetase from Pseudomonas sp.

≥2 units/mg protein

Sinónimos:

Acid: CoA ligase (AMP-forming)

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Talla/SKUDisponibilidadPrecio
1 unit
Comprobar disponibilidad del carrito
US$ 355,00
10 units
Comprobar disponibilidad del carrito
US$ 1.760,00

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Número CAS:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-747-5
MDL number:
Número CE:
Specific activity:
≥2 units/mg protein

US$ 355,00

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form

powder

Quality Segment

specific activity

≥2 units/mg protein

shipped in

dry ice

storage temp.

−20°C

General description

Acyl-coenzyme A synthetase belongs to adenylate-forming enzymes superfamily. It has a conserved adenosine triphosphate/adenosine monophosphate (ATP/AMP) binding motif.

Application

Acyl-coenzyme A Synthetase may be used to study fatty acid metabolism and lipid metabolism. It has been used to study its interaction with fatty acid transport proteins, which has been found to be involved in the efficient cellular uptake of long-chain fatty acids in adipocytes .
Acyl-coenzyme A (coA) synthetase from Pseudomonas sp. has been used:
  • as ligase in the synthesis of mevalonate derivatives of adenosine triphosphate (ATP)
  • in in vitro fatty acylation assays
  • in the synthesis of (14C)Vernoloyl-CoA (Va-CoA),(3) bisphosphonates derivatives of ATP(4) and (3H)Palmitate-CoA

Biochem/physiol Actions

Acyl coenzyme A synthetase proteins are involved in regulating and facilitating long-chain fatty acid transport in mammalian cells .
Acyl-coenzyme A (CoA) synthetase (ACS) enzyme catalyzes a two-step thioesterification reaction involving the conversion of free fatty acids (FAs) to CoA esters. The substrate for ACS varies from two carbon to 26 carbon FAs. It is involved in the activation of FAs for lipid metabolism and enables FA to participate in various cellular metabolic pathways.

Other Notes

One unit will form 1.0 μmole of AMP and oleoyl coenzyme A from ATP and oleate at pH 8.1 at 25 °C in the presence of Coenzyme A.

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Este artículo
C4780L2659H2012
description

≥2 units/mg protein

description

BioReagent, suitable for cell culture

description

≥90% (HPLC)

description

≥85%

specific activity

≥2 units/mg protein

specific activity

-

specific activity

-

specific activity

-

form

powder

form

powder

form

-

form

-

shipped in

dry ice

shipped in

-

shipped in

-

shipped in

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


Clase de almacenamiento

11 - Combustible Solids

¿Qué está pasando?

WGK 3

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)

Not applicable

EPI (equipos de protección individual)

Eyeshields, Gloves, type N95 (US)



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