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94259

Sigma-Aldrich

(±)-Mevalonic acid 5-pyrophosphate tetralithium salt

≥80% (qNMR)

Sinónimos:

(±)-MVAPP, (±)-Mevalonic acid 5-diphosphate tetralithium salt

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About This Item

Fórmula empírica (notación de Hill):
C6H10Li4O10P2
Número de CAS:
108869-00-7
Peso molecular:
331.85
MDL number:
MFCD16875404
UNSPSC Code:
12352201
PubChem Substance ID:
329770318
NACRES:
NA.25

assay

≥80% (qNMR)

form

powder

color

white

storage temp.

−20°C

SMILES string

[Li+].[Li+].[Li+].[Li+].CC(O)(CCOP([O-])(=O)OP([O-])([O-])=O)CC([O-])=O

InChI

1S/C6H14O10P2.4Li/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12);;;;/q;4*+1/p-4

InChI key

GFIXUUFXTAPBAD-UHFFFAOYSA-J

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Categorías relacionadas

Biochem/physiol Actions

Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase. Mevalonic acid 5-pyrophosphate was shown to elevate ubiquinone levels in rat liver tissues.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

M4667

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Proceedings of the National Academy of Sciences of the United States of America, 112(31), 9781-9786 (2015-07-23)
Rhizobia and arbuscular mycorrhizal fungi produce signals that are perceived by host legume receptors at the plasma membrane and trigger sustained oscillations of the nuclear and perinuclear Ca(2+) concentration (Ca(2+) spiking), which in turn leads to gene expression and downstream
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Procedures for the isolation and analysis of all 11 intermediates of the mevalonic acid pathway from acetyl-CoA through geranylgeranyl pyrophosphate were developed. Both acid-labile and base-labile metabolites are simultaneously extracted with good recoveries into 7 M urea at neutral pH

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