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85578

Spermidine trihydrochloride

Name: Spermidine trihydrochloride
Brand: SIGMA
Price: 83.1 USD

BioXtra, ≥99.5% (AT)

Sinónimos:

N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride

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A ustedes/SKU	Disponibilidad	Precio
1 g	Comprobar disponibilidad del carrito	US$ 83,10
5 g	Comprobar disponibilidad del carrito	US$ 309,00

Acerca de este artículo

Fórmula lineal:

NH₂(CH₂)₃NH(CH₂)₄NH₂ · 3HCl

Número CAS:

334-50-9

Peso molecular:

254.63

UNSPSC Code:

12352116

NACRES:

NA.26

PubChem Substance ID:

57653005

EC Number:

206-379-0

Beilstein/REAXYS Number:

3552356

MDL number:

MFCD00012918

US$ 83,10

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Propiedades

product line

BioXtra

Quality Segment

100

assay

≥99.0% (TLC), ≥99.5% (AT)

form

powder

impurities

insoluble matter, passes filter test

pH

3.0-6.0 (25 °C, 1 M in H₂O)

mp

257-259 °C (lit.)

solubility

H₂O: 1 M at 20 °C, clear, colorless

anion traces

sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤10 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

1 M in H₂O

UV absorption

λ: 260 nm A_max: 0.2, λ: 280 nm A_max: 0.1

SMILES string

Cl[H].Cl[H].Cl[H].NCCCCNCCCN

InChI

1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H

InChI key

LCNBIHVSOPXFMR-UHFFFAOYSA-N

Descripción

General description

Spermidine trihydrochloride is an aliphatic polyamine. Its crystalline structure has been studied. It has been reported to preserve the nuclei and prevent proteolytic degradation of histones during the macronuclei isolation from Tetrahymena pyriformis.

Application

Spermidine trihydrochloride is used for the following applications:

DNA extraction and restriction endonuclease digestion
Nuclear transplantation
During the chemical analyses of the squid species Todaropsis eblanae
As one of the agents in intercalating drug.
Platelet aggregation

It may be used in the synthesis of palladium complexes like [sperH₃]₂[PdCl₄]₃, [PdCl₂(sperH)]₂[PdCl₄], and [(PdCl₂)₃(sper)₂] by reacting with K₂PdCl₄ and PdCl₂.

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Other Notes

Buffer component for chromosome isolation in bivariate flow cytogenetic analysis and sorting.

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

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Este artículo	56766M	S2501	85605
Sigma-Aldrich 85578 Spermidine trihydrochloride	Sigma-Aldrich 56766M Spermidine, Trihydrochloride	Sigma-Aldrich S2501 Spermidine trihydrochloride	Sigma-Aldrich 85605 Spermine tetrahydrochloride
description BioXtra, ≥99.5% (AT)	description Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.	description ≥98% (TLC)	description BioUltra, Molecular Biology, ≥99.5% (AT)
assay ≥99.0% (TLC), ≥99.5% (AT)	assay ≥98% (TLC)	assay ≥98% (TLC)	assay ≥99.5% (AT)
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 300
form powder	form solid	form powder	form powder
solubility H₂O: 1 M at 20 °C, clear, colorless	solubility ethanol: soluble, water: soluble	solubility water: 100 mg/mL, clear, colorless	solubility H₂O: 1 m at 20 °C, clear, colorless to almost colorless
mp 257-259 °C (lit.)	mp -	mp 257-259 °C (lit.)	mp 310-311 °C (dec.) (lit.)
cation traces Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Ca: ≤10 mg/kg, Co: ≤5 mg/kg, Cu: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mo: ≤5 mg/kg, Ni: ≤5 mg/kg, Sr: ≤5 mg/kg, As: ≤0.1 mg/kg, Cd: ≤5 mg/kg, Fe: ≤5 mg/kg, Mn: ≤5 mg/kg, Pb: ≤10 mg/kg, Bi: ≤5 mg/kg, Li: ≤5 mg/kg, Zn: ≤5 mg/kg, Cr: ≤5 mg/kg, Na: ≤50 mg/kg	cation traces -	cation traces -	cation traces Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319

pcodes

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c