Metabolite of fructose, mannose, and fucose metabolism, present in microbial metabolism in diverse environments.
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In humans, the gene encoding a reverse thymidylate synthase (rTS) is transcribed in the reverse direction of the gene encoding thymidylate synthase (TS) that is involved in DNA biosynthesis. Three isoforms are found: α, β, and γ, with the transcript
Proceedings of the National Academy of Sciences of the United States of America, 108(17), 7194-7199 (2011-04-13)
Campylobacter jejuni is a prevalent gastrointestinal pathogen in humans and a common commensal of poultry. When colonizing its hosts, C. jejuni comes into contact with intestinal carbohydrates, including L-fucose, released from mucin glycoproteins. Several strains of C. jejuni possess a
Microorganisms producing L-fucose dehydrogenase were screened from soil samples, and one of the isolated bacterial strains SA-134 was identified as Acinetobacter sp. by 16S rDNA gene analysis. The strain grew well utilizing L-fucose as a sole source of carbon, but
L-Fucose metabolism in mammals. I. Port liver L-fuconate hydro-lyase.
R Yuen et al.
Canadian journal of biochemistry, 50(7), 798-806 (1972-07-01)
Many members of the mechanistically diverse enolase superfamily have unknown functions. In this report we use both genome (operon) context and screening of a library of acid sugars to assign the L-fuconate dehydratase (FucD) function to a member of the
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