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Documentos

06372

Sigma-Aldrich

β-Hydroxypyruvic acid

≥95.0% (dry substance, T)

Sinónimos:

3-Hydroxy-2-oxopropanoic acid

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About This Item

Fórmula empírica (notación de Hill):
C3H4O4
Número de CAS:
1113-60-6
Peso molecular:
104.06
MDL number:
MFCD00083380
UNSPSC Code:
12352204
PubChem Substance ID:
329748234
NACRES:
NA.32

assay

≥95.0% (dry substance, T)

form

powder and chunks

impurities

≤15.0% water

storage temp.

2-8°C

SMILES string

OC(C(CO)=O)=O

InChI

1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7)

InChI key

HHDDCCUIIUWNGJ-UHFFFAOYSA-N

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Application


  • Hydroxy(phenyl)pyruvic acid reductase in Actaea racemosa L.: a putative enzyme in cimicifugic and fukinolic acid biosynthesis.: This study investigates the role of ß-Hydroxypyruvic acid in the biosynthesis of bioactive compounds in Actaea racemosa, highlighting its importance in plant secondary metabolism and potential applications in medicinal chemistry (Jahn and Petersen, 2024).

  • The gut microbiota confers protection in the CNS against neurodegeneration induced by manganism.: Research shows the protective role of ß-Hydroxypyruvic acid derivatives produced by gut microbiota against neurodegenerative conditions, providing insights into therapeutic strategies for neurological disorders (Wang et al., 2020).

Biochem/physiol Actions

Metabolite involved in the pathway of carbon in photorespiration.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

hcodes

H302,H314

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Phenylpyruvic acid 98%

Sigma-Aldrich

286958

Phenylpyruvic acid

USP

USP

1204102

Dihydroxyacetone

Bromopyruvic acid ≥98.0%

Sigma-Aldrich

16490

Bromopyruvic acid

Dihydroxyacetone for synthesis

Sigma-Aldrich

8.20482

Dihydroxyacetone

Dihydroxyacetone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1430

Dihydroxyacetone

O A Esakova et al.
IUBMB life, 59(2), 104-109 (2007-04-25)
The interaction of thiamine diphosphate (ThDP) with transketolase (TK) involves at least two stages: [formula: see text] During the first stage, an inactive intermediate complex (TK...ThDP) is formed, which is then transformed into a catalytically active holoenzyme (TK* - ThDP).
M Legge
Biochimica et biophysica acta, 1355(2), 99-101 (1997-02-04)
Mouse oocytes and zygotes, when solubilised demonstrated that a range of ketoaldehydes could be utilised as substrates. Of the five ketoaldehydes investigated the overall substrate utilisation was hydroxypyruvate > glyoxylate > 2-ketobutyrate > pyruvate > glycolate. The utilisation of these
William E Karsten et al.
Biochimica et biophysica acta, 1790(6), 575-580 (2009-03-07)
The enzyme L-serine-glyoxylate aminotransferase (SGAT) from Hyphomicrobium methylovorum is a PLP-containing enzyme that catalyzes the conversion of L-serine and glyoxylate to hydroxypyruvate and glycine. The cloned enzyme expressed in Escherichia coli is isolated as a mixture of the E:PLP and
Shweta Joshi et al.
Molecular and biochemical parasitology, 160(1), 32-41 (2008-05-06)
The pentose phosphate pathway (PPP) is an important metabolic pathway for yielding reducing power in the form of NADPH and production of pentose sugar needed for nucleic acid synthesis. Transketolase, the key enzyme of non-oxidative arm of PPP, plays a
M C Lawrence et al.
Journal of molecular biology, 266(2), 381-399 (1997-02-21)
We describe here a sub-family of enzymes related both structurally and functionally to N-acetylneuraminate lyase. Two members of this family (N-acetylneuraminate lyase and dihydrodipicolinate synthase) have known three-dimensional structures and we now proceed to show their structural and functional relationship
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