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Merck

Y0001053

Crospovidone

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Polyvinylpyrrolidone, PVP, Polyvidone, Povidone

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About This Item

Fórmula lineal:
(C6H9NO)n
Número de CAS:
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

crospovidone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Crospovidone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.
Sales restrictions may apply.

related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Patricia C Buchsel
Expert opinion on drug metabolism & toxicology, 4(11), 1449-1454 (2008-10-28)
Painful oral lesions in patients with cancer, HIV or aphthous ulcers can cause significant pain and discomfort. Those with oral mucositis (OM) resulting from high-dose chemotherapy or irradiation are the most at risk for painful lesions that lead to significant
Polyvinylpyrrolidone (PVP), its diagnostic, therapeutic and technical application and consequences thereof.
W Wessel et al.
Arzneimittel-Forschung, 21(10), 1468-1482 (1971-10-01)
Atsuko Adachi et al.
Contact dermatitis, 48(3), 133-136 (2003-05-21)
A 59-year-old woman who had had several episodes of contact urticaria after hair treatment, developed anaphylaxis after vaginal application of povidone-iodine solution for disinfection. Prick tests showed wheal-and-flare responses to both povidone-iodine (0.1% aqueous) and polyvinylpyrrolidone (povidone, PVP) (0.001% aq.)
J L Zamora
American journal of surgery, 151(3), 400-406 (1986-03-01)
The chemical, microbiologic, and toxic characteristics of povidone-iodine solution, a commonly used antiseptic agent, are addressed in a collective review of relevant works published from 1956 to the present. Interactions of this agent with the thyroid gland and the kidneys
Eduardo Caldelas Cuéllar et al.
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The jumper's knee or patellar tendonitis is a common injury in the athlete with an incidence between 14% and 16% among high-performance athletes. In addition to an overuse injury, there are some intrinsic factors for its development. Conservative treatment is

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