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Merck

R2751

Sigma-Aldrich

Ruthenium Red

Powder

Sinónimos:

Ammoniated ruthenium oxychloride

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About This Item

Fórmula lineal:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
Número de CAS:
Peso molecular:
786.35
Colour Index Number:
77800
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Ruthenium Red, Technical grade

Quality Level

assay

34-39% (RUTHENIUM, ICP)

form

powder

solubility

water: 10 mg/mL

εmax

≥150 at 533-534 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]

InChI

1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6

InChI key

ZXYSDUPLHOJIOR-UHFFFAOYSA-H

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General description

Ruthenium Red is a hexavalent polysaccharide stain. It inhibits mitochondrial Ca2+ uniporter. It is a capsaicin antagonist and blocks vanilloid receptor-1 (VR-1)-coupled ion channels.

Application

Ruthenium Red has been used for microscopic characterization of cotton tip morphology. It has also been used as a TRPV2 channel blocker.
Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Cotton fiber tips have diverse morphologies and show evidence of apical cell wall synthesis
Michael R. Stiff and Candace H. Haigler
Scientific Reports (2016)
Ruthenium red as a capsaicin antagonist.
Amann R and Maggi CA
Life Sciences, 49(12) (1991)
TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells
Yuan Wang
Oncotarget, 7(32) (2016)
Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release
Jae Hoon Bae
Biochemical and Biophysical Research Communications, 303 (2003)
George Goodwin et al.
Neuroscience, 429, 10-22 (2019-12-25)
Radiating pain is a significant feature of chronic musculoskeletal pain conditions such as radiculopathies, repetitive motion disorders and whiplash associated disorders. It is reported to be caused by the development of mechanically-sensitive ectopic receptive fields along intact nociceptor axons at

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