It is suggested to use 15 to 30 units per mL of blood.
H4784
Heparina sodium salt from porcine intestinal mucosa
≥180 USP units/mg
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About This Item
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Productos recomendados
origen biológico
Porcine intestinal mucosa
Nivel de calidad
Formulario
powder
actividad específica
≥180 USP units/mg
solubilidad
H2O: 50 mg/mL, clear, colorless to faintly yellow
trazas de catión
Ca: ≤20 ppm
temp. de almacenamiento
2-8°C
cadena SMILES
[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
Clave InChI
JRTRSJGZMRQDHI-UHFFFAOYSA-N
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Descripción general
Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Calidad
Low calcium content
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
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Certificados de análisis (COA)
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William H Thiel et al.
PloS one, 7(9), e43836-e43836 (2012-09-11)
The broad applicability of RNA aptamers as cell-specific delivery tools for therapeutic reagents depends on the ability to identify aptamer sequences that selectively access the cytoplasm of distinct cell types. Towards this end, we have developed a novel approach that
Xiaofeng Ye et al.
PloS one, 8(1), e54622-e54622 (2013-01-30)
The application of polyelectrolyte multilayer films is a new, versatile approach to surface modification of decellularized tissue, which has the potential to greatly enhance the functionality of engineered tissue constructs derived from decellularized organs. In the present study, we test
Linda Cruz et al.
PloS one, 8(7), e68379-e68379 (2013-07-19)
Human papillomavirus (HPV) infection is the leading cause of cervical cancer world-wide. Here, we show that native HPV particles produced in a differentiated epithelium have developed different strategies to infect the host. Using biochemical inhibition assays and glycosaminoglycan (GAG)-negative cells
Eve Draper et al.
PloS one, 8(5), e61825-e61825 (2013-05-08)
The current generation of Human Papillomavirus (HPV) vaccines, Cervarix® and Gardasil®, exhibit a high degree of efficacy in clinical trials against the two high-risk (HR) genotypes represented in the vaccines (HPV16 and HPV18). High levels of neutralizing antibodies are elicited
Anqi Huang et al.
eLife, 9 (2020-02-13)
During development, many mutations cause increased variation in phenotypic outcomes, a phenomenon termed decanalization. Phenotypic discordance is often observed in the absence of genetic and environmental variations, but the mechanisms underlying such inter-individual phenotypic discordance remain elusive. Here, using the
Artículos
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
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How much Heparin sodium salt, is used to prevent coagulation?
1 answer-
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What is the best way to sterilize Heparin sodium salt?
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Although solutions may be autoclaved at 121 °C for 5 to 10 minutes, we generally recommend sterile filtration. This is because prolonged autoclaving may have an effect on its activity.
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What concentration of Heparin sodium salt, can I use to inhibit RNAse activity?
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Heparin has been used at concentrations ranging from 100 to 500 μg/mL. This has been reported in the J. Biol. Chem., 248, 2095 (1973).
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How does the storage temperature relate to shipping conditions?
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The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.
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What concentration of Product H4784, Heparin sodium salt, is used in cell culture for the cultivation of human epidermal melanocytes in absence of phorbol esters?
1 answer-
Heparin is used at a concentration of 1 ng/mL, according to Picot, J., Human Cell Culture: Methods in Molecular Medicine, 2nd ed., (Humana Press Inc., 2005) pp. 13-28.
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What is the molecular weight of Heparin sodium salt?
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Heparin is a mixture of polyanion chains having molecular weights ranging from 6,000 to 30,000 Daltons, with most chains in the range of 17,000 to 19,000 Daltons.
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What is the pH of a 1% solution of Product H4784, Heparin sodium salt?
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The pH of 1% solution of heparin sodium salt is typically in the range of 6.0 to 7.5.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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