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BCR096

Dibenzo[a,l]pyrene

BCR®, certified reference material

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About This Item

Fórmula empírica (notación de Hill):
C24H14
Número de CAS:
191-30-0
Peso molecular:
302.37
Beilstein/REAXYS Number:
2054068
MDL number:
MFCD00467035
UNSPSC Code:
41116107
PubChem Substance ID:
329774220
NACRES:
NA.24

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

c1ccc2c(c1)cc3ccc4cccc5c6ccccc6c2c3c45

InChI

1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H

InChI key

JNTHRSHGARDABO-UHFFFAOYSA-N

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Analysis Note

For more information please see:
BCR096

Legal Information

BCR is a registered trademark of European Commission

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Carc. 1B - Eye Dam. 1 - Muta. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Joseph B Guttenplan et al.
International journal of cancer, 130(12), 2783-2790 (2011-08-05)
Cancer of the oral cavity is a serious disease, affecting about 30,000 individuals in US annually. There are several animal models of oral cancer, but each has certain disadvantages. As a new model, we investigated whether topical application of the
David M DeMarini et al.
Mutation research, 714(1-2), 17-25 (2011-06-22)
Benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP) are two polycyclic aromatic hydrocarbons (PAHs) that exhibit distinctly different mutagenicity and carcinogenicity profiles. Although some studies show that these PAHs produce unstable DNA adducts, conflicting data and arguments have been presented regarding the relative
Ian W H Jarvis et al.
Toxicology and applied pharmacology, 266(3), 408-418 (2012-12-12)
Complex mixtures of polycyclic aromatic hydrocarbons (PAHs) are present in air particulate matter (PM) and have been associated with many adverse human health effects including cancer and respiratory disease. However, due to their complexity, the risk of exposure to mixtures
Tammie J McQuistan et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(2), 341-352 (2011-11-15)
Recent pilot studies found natural chlorophyll (Chl) to inhibit carcinogen uptake and tumorigenesis in rodent and fish models, and to alter uptake and biodistribution of trace (14)C-aflatoxin B1 in human volunteers. The present study extends these promising findings, using a
Yijin Tang et al.
Biochemistry, 51(48), 9751-9762 (2012-11-06)
The most potent tumorigen identified among the polycyclic aromatic hydrocarbons (PAH) is the nonplanar fjord region dibenzo[a,l]pyrene (DB[a,l]P). It is metabolically activated in vivo through the widely studied diol epoxide (DE) pathway to form covalent adducts with DNA bases, predominantly
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