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A5131

Sigma-Aldrich

L-arginina monohydrochloride

≥98% (HPLC)

Sinónimos:

(S)-(+)-arginina hydrochloride

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About This Item

Fórmula empírica (notación de Hill):
C6H14N4O2 · HCl
Número de CAS:
1119-34-2
Peso molecular:
210.66
Beilstein/REAXYS Number:
3631658
EC Number:
214-275-1
MDL number:
MFCD00064550
UNSPSC Code:
12352209
PubChem Substance ID:
24890944
NACRES:
NA.26
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Nombre del producto

L-arginina monohydrochloride, reagent grade, ≥98% (HPLC), powder

grade

reagent grade

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white

mp

>235 °C

solubility

H2O: 50 mg/mL

application(s)

cell analysis

SMILES string

Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1

InChI key

KWTQSFXGGICVPE-WCCKRBBISA-N

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Application

El monoclorhidrato de L-arginina se ha utilizado para estudiar los efectos de los aminoácidos en la promoción del consumo de alimentos en Drosophila melanogaster. También se ha utilizado para desarrollar un modelo de pancreatitis crónica no invasiva de rata.[1][2]

Biochem/physiol Actions

La L-arginina es un aminoácido semiesencial. Este aminoácido dibásico actúa como precursor de la creatinina y es un constituyente natural de la mayoría de las proteínas alimentarias.[3]
Sustrato de la óxido nítrico sintasa, que se convierte en citrulina y óxido nítrico (NO). Induce la liberación de insulina mediante un mecanismo dependiente del óxido nítrico.

Comparable product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000417335
0000417335
0000414298
0000414298
0000406874

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Severe Chronic Pancreatitis due to Recurrent Acute Injury: Non-Invasive Chronic Pancreatitis Model of Rat
Surendra Sharma
Pancreas (2016)
J. P. Felix D'Mello
Amino Acids in Human Nutrition and Health (2012)
Enyong Dai et al.
Nature communications, 11(1), 6339-6339 (2020-12-15)
Ferroptosis is a more recently recognized form of cell death that relies on iron-mediated oxidative damage. Here, we evaluate the impact of high-iron diets or depletion of Gpx4, an antioxidant enzyme reported as an important ferroptosis suppressor, in the pancreas
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature (2017)
Jiao Liu et al.
Nature communications, 12(1), 647-647 (2021-01-30)
Ferroptosis is a type of iron-dependent regulated cell death, representing an emerging disease-modulatory mechanism. Transcription factors play multiple roles in ferroptosis, although the key regulator for ferroptosis in iron metabolism remains elusive. Using NanoString technology, we identify NUPR1, a stress-inducible
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Questions

1–7 of 7 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Ho bisogno di l-arginina cloridrato ≥98,5 % soluzione per via endovenosa, è disponibile?

    1 answer

    1. This product is listed for research use only and is not suitable for human or animal use. There are no products available for intravenous use in any form.

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  4. Are solutions of Product No. A5131 (L-Arginine monohydrochloride) autoclavable?

    1 answer

    1. Arginine is routinely autoclaved as a component of microbial media with no adverse effects; therefore solutions of A5131 L-Arginine monohydrochloride may be autoclaved.

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  5. What is the method of preparation process for the A5131 L-Arginine monohydrochloride?

    1 answer

    1. No animal proteins or products are used in the fermentation process or purification of the L-Arginine.

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  6. What are the solubility properties of L-Arginine monohydrochloride (Product No. A5131)?

    1 answer

    1. L-Arginine monohydrochloride is soluble in water at a concentration of 1M (210 mg/mL).

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  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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