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66720

Sigma-Aldrich

Methylene Blue hydrate

purum p.a., for microscopy (Bact., Bot., Hist., Vit.), ≥97.0% (calc. based on dry substance, AT)

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About This Item

Fórmula empírica (notación de Hill):
C16H18ClN3S · xH2O
Número de CAS:
122965-43-9
Peso molecular:
319.85 (anhydrous basis)
Beilstein/REAXYS Number:
3599847
EC Number:
200-515-2
MDL number:
MFCD00150006
UNSPSC Code:
12171500
PubChem Substance ID:
329760310
NACRES:
NA.32

grade

for microscopy (Bact., Bot., Hist., Vit.)
purum p.a.

Quality Level

200

assay

≥97.0% (calc. based on dry substance, AT)

SMILES string

O.[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C

InChI

1S/C16H18N3S.ClH.H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;/h5-10H,1-4H3;1H;1H2/q+1;;/p-1

InChI key

WQVSELLRAGBDLX-UHFFFAOYSA-M

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Categorías relacionadas

General description

Methylene Blue (MB) is a basic histological dye.

Application

Methylene Blue hydrate has been used:
  • in the preparation of methylene blue (MB) solution to stain zymograms
  • to label the injection site in the tissue slices
  • to pre-treat mice via oral gavage to study its effects on noise-induced hearing loss

Biochem/physiol Actions

Methylene blue (MB) plays a key role in microbiology and pharmacology. It is mainly used in staining live organisms and in methemoglobinemia treatment. MB can be considered as a possible and safe vasoconstrictor. It has several applications in textile, paper and hair coloring sectors.

Other Notes

may contain up to 22% water
On the efficiency of methylene blue versus persulfate catalysis of polyacrylamide gels, as investigated by capillary zone electrophoresis

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCM4231
BCCH3435
BCCK3438
BCCD9107
BCBZ4929

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Methylene blue in the treatment of vasodilatory shock: a Meta-analysis
Zhang X, et al.
Zhonghua Wei Zhong Bing ji Jiu yi Xue, 2(3), 175-191 (2017)
Preparation and analysis of crude autolytic enzyme extracts from Staphylococcus aureus
Vaz F, et al.
Bio-protocol, 5(3), e1687-e1687 (2015)
Attenuation of noise-induced hearing loss using methylene blue
Park JS, et al.
Cell Death & Disease, 5(4), e1200-e1200 (2014)
S Caglio et al.
Electrophoresis, 14(10), 997-1003 (1993-10-01)
The efficiency of a novel method of photopolymerization, based on photoinitiating the reaction with methylene blue (MB), in presence of a redox couple (sodium toluenesulfinate and diphenyliodonium chloride), vs, the conventional persulfate--N,N,N',N'-tetramethylethylenediamine redox couple was investigated as a function of
Efficient removal of different basic dyes using graphene
Iqbala MZ, et al.
Desalination and Water Treatment, 68(3), 226-235 (2017)
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