FCABS165A6

Milli-Mark^® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate

Milli-Mark^®, from rabbit

• Sinónimos: Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, MAP kinase isoform p44, p44, MAPK, Microtubule-associated protein 2 kinase, MNK1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: ALEXA FLUOR^™ 647
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• reactividad de especies: human
• fabricante / nombre comercial: Milli-Mark^®
• técnicas: flow cytometry: suitable
• Nº de acceso NCBI: NP_059043
• Nº de acceso UniProt: P21708
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... MAPK1(5594)

Descripción

Descripción general

The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.

Especificidad

Antibody recognizes MAPK1/2. C-terminus.

Inmunógeno

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.

Aplicación

Milli-Mark Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate detects level of MAPK 1/2 (tERK) & has been published & validated for use in FC.

Research Category
Signaling

Research Sub Category
MAP Kinases

Calidad

Evaluated by flow cytometry using Jurkat cells

Descripción de destino

43 kDa Calculated

Forma física

Protein A purified

Purified rabbit polyclonal antibody conjugated to Alexa Fluor 647 in PBS buffer with 15mg/mL BSA and 0.1% Sodium Azide

Almacenamiento y estabilidad

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Nota de análisis

Control
Jurkat cells

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

ALEXA FLUOR is a trademark of Life Technologies

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable